Mindfulness and Meditation-Based Relapse Prevention for Substance Use Disorders

NCT07417579 | Completed

• 1 other identifier: BMH-MBRP-OBS-001
• Study Type: observational
• Target: 3
• Locations: 1 country
• Sites: 1

Brief Summary

Mindfulness and meditation based relapse prevention has been proposed as an adjunctive approach for individuals with substance use disorders (SUDs). This completed pilot observational case series describes outcomes from three de-identified participants who completed an eight-week mindfulness and meditation program designed to reduce stress, enhance coping skills, and support sustained recovery. Participants demonstrated improvements in perceived stress and mindfulness following the intervention. Two participants experienced relapse within 10-12 months, while one participant maintained long-term sobriety. This small case series provides descriptive clinical insights and supports the feasibility of mindfulness-based interventions in real-world treatment settings.

Conditions

Substance Use Disorders; Behavioral Health; Addiction Psychological; Addiction Disorders; Meditation; Mindfulness Based Stress Reduction; Prevention

Keywords

mindfulness; meditation; relapse prevention; substance use; behavioral health; addiction recovery

Outcome Measures

Primary Outcomes (1)

• Change in Perceived Stress and Mindfulness Following Mindfulness-Based Relapse Prevention Program

  The primary outcome is the change in perceived stress and mindfulness levels in participants completing an eight-week mindfulness and meditation-based relapse prevention program. Stress was assessed using the Perceived Stress Scale and mindfulness using the Five Facet Mindfulness Questionnaire. Observations were collected through participant journals and clinical interviews, comparing baseline to post-intervention outcomes. This outcome reflects the feasibility and potential impact of mindfulness-based practices in supporting emotional regulation and coping strategies for individuals with substance use disorders.

  Baseline (pre-intervention) to end of the eight-week program

Study Arms (1)

Mindfulness-Based Relapse Prevention Case Series

This cohort includes three adult participants with histories of substance use disorders who completed an eight-week mindfulness and meditation-based relapse prevention program delivered as part of routine clinical practice. Participants engaged in guided mindfulness meditation sessions, daily home practice, and group discussions focused on stress awareness, emotional regulation, craving management, and relapse prevention skills. Outcomes were assessed descriptively using self-reported stress and mindfulness measures, participant journals, and clinical interviews.

Behavioral: Mindfulness and Meditation-Based Relapse Prevention Program

Interventions

Mindfulness and Meditation-Based Relapse Prevention Program BEHAVIORAL

The mindfulness and meditation-based relapse prevention program consisted of an eight-week structured intervention delivered as part of routine clinical practice. Participants engaged in weekly guided mindfulness meditation sessions, daily individual home practice, and facilitated group discussions. The intervention focused on developing awareness of thoughts, emotions, cravings, and stress responses, with an emphasis on nonjudgmental observation and emotional regulation. Sessions included mindfulness exercises, breathing techniques, body awareness practices, and reflective discussion related to relapse prevention and coping strategies. The program was not designed as a randomized or controlled intervention and was implemented uniformly across participants.

Mindfulness-Based Relapse Prevention Case Series

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of three de-identified adults with a history of substance use disorders who participated in an eight-week mindfulness and meditation based relapse prevention program. Participants included two females and one male, ranging in age from 30 to 51 years. All participants engaged in weekly guided sessions, daily home practice, and group discussions. The population was selected from individuals already enrolled in the program and willing to participate in data collection for observational purposes. No restrictions were placed on sex beyond adult eligibility, and participants had varying substance use histories and prior treatment experiences.

You may qualify if:

• Adults aged 18 years or older
• History of substance use disorder (any substance)
• Enrolled in or referred to an eight-week mindfulness and meditation-based relapse prevention program
• Willing and able to participate in weekly guided sessions, daily home practice, and group discussions
• Able to provide self-reported information on stress, mindfulness, and relapse experiences

You may not qualify if:

• Individuals under 18 years of age
• Inability or unwillingness to participate in mindfulness or meditation exercises
• Severe cognitive impairment or psychiatric condition preventing participation in group or home practice
• Participation in concurrent structured relapse prevention programs outside of this study

Sponsors & Collaborators

• Bout Me Healing: lead

Study Sites (1)

Bout Me Healing

Boca Raton, Florida, 33496, United States

Location

Related Publications (1)

• Rivera, Cice (2026). Mindfulness and Meditation-Based Relapse Prevention for Substance Use Disorders: Research Case Series of Three Participants. figshare. Journal contribution. https://doi.org/10.6084/m9.figshare.31302370.v1

  RESULT

Related Links

• De-identified participant data, study protocol, and clinical report will be shared with qualified researchers upon request for 3 years following publication.

MeSH Terms

Conditions

Substance-Related Disorders

Interventions

Mindfulness

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Cognitive Behavioral Therapy; Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Cice Rivera, MS, CAP

  Bout Me Healing

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 11, 2026
• First Posted: February 18, 2026
• Study Start: January 15, 2015
• Primary Completion: March 11, 2015
• Study Completion: March 11, 2016
• Last Updated: February 18, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ICF, CSR
• Time Frame: The individual participant data (IPD) and supporting documents will be available starting from the date the study record becomes publicly accessible on ClinicalTrials.gov and will remain available for three years following publication.
• Access Criteria: IPD will be accessible to qualified researchers who submit a request with a research proposal and agree to a data use agreement. Available materials include de-identified participant data (stress scores, mindfulness scores, relapse observations), the study protocol, and the clinical study report. Data access will be granted following review to ensure ethical use and confidentiality protection.

Locations

US (1)