NCT07411859

Brief Summary

This study will examine the effectiveness of tDCS (Transcranial Direct Current Stimulation) in reducing chronic pain when used with Emory Healthcare Veterans Program (EHVP)-ABHP (Accelerated Behavioral Health Program) participants as measured by the Pain, Enjoyment of Life and General Activity Scale (PEG).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable chronic-pain

Timeline
12mo left

Started Feb 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress22%
Feb 2026May 2027

First Submitted

Initial submission to the registry

February 9, 2026

Completed
7 days until next milestone

Study Start

First participant enrolled

February 16, 2026

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 17, 2026

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2027

Last Updated

April 14, 2026

Status Verified

April 1, 2026

Enrollment Period

1.2 years

First QC Date

February 9, 2026

Last Update Submit

April 13, 2026

Conditions

Chronic Pain

Outcome Measures

Primary Outcomes (1)

  • Change in PEG (Pain, Enjoyment of Life and General Activity) scale

    The PEG scale includes 3 questions each rated from 0 (no pain) to 10 (Pain as bad as you can imagine) over the past 24 hours. Items include average pain, interference in enjoyment, and interference in general activity. Higher score correlates with worse study outcome.

    Baseline, day 12 post-intervention (end of treatment)

Secondary Outcomes (1)

  • Change in PEG scale

    Baseline, 3,6, and 12 months post-intervention

Study Arms (1)

Transcranial Direct Current Stimulation (tDCS) plus accelerated Behavioral Health Program

EXPERIMENTAL

Participants will receive short, daily tDCS treatment sessions for two weeks. Starting Day 1, tDCS will be administered with a constant current intensity of 2 mA for 20 min per session for up to 10 sessions over 2 weeks.

Device: Transcranial Direct Current Stimulation

Interventions

Transcranial Direct Current StimulationDEVICE

tDCS is a painless brain stimulation treatment that uses direct electrical currents (at a constant, low intensity level) to stimulate specific parts of the brain and help modulate neuronal activity. Participants will receive a series of tDCS treatments during the Accelerated Brain Health Program (ABHP) coupled with self-report of pain severity and interference tDCS has been used to improve cognitive functions and pain management. Starting Day 1 of EHVP-IOP, tDCS will be administered with a constant current intensity of 2 mA for 20 min per session for up to 10 sessions over 2 weeks

Also known as: tDCS
Transcranial Direct Current Stimulation (tDCS) plus accelerated Behavioral Health Program

Eligibility Criteria

Age18 Years - 89 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male or Female, 18-89 years old
  • Treated on site for ABHP
  • Willing to self-administer tDCS and complete the measures
  • PEG pain intensity of 4 or more for most of the day at least 3 days per week
  • Have an established PCP (Primary Care Provider) or pain management provider

You may not qualify if:

  • Implanted pacemaker
  • Seizure Disorder
  • Pregnancy, if applicable
  • Any new onset of the following:
  • Balance Problems
  • Difficulty walking
  • Bladder incontinence
  • Bowel incontinence
  • Numbness
  • Tingling
  • Weakness
  • Medical contraindications
  • Current use of sodium channel blockers
  • Lidocaine (OTC/transdermal delivery is ok)
  • Mexiletine
  • +16 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Emory Clinic

Atlanta, Georgia, 30308, United States

RECRUITING

MeSH Terms

Conditions

Chronic Pain

Interventions

Transcranial Direct Current Stimulation

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsConvulsive TherapyPsychiatric Somatic TherapiesBehavioral Disciplines and ActivitiesElectroshockPsychological Techniques

Study Officials

  • Sheila Rauch, PhD

    Emory University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Syreese Fuller

CONTACT

404-778-3188syreese.fuller@emory.edu

Sheila Rauch, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 9, 2026

First Posted

February 17, 2026

Study Start

February 16, 2026

Primary Completion (Estimated)

May 1, 2027

Study Completion (Estimated)

May 1, 2027

Last Updated

April 14, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

US(1)