NCT07408245

Brief Summary

The primary purpose of this study is to evaluate the effects of Biocidin liquid on oral biofilms among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of two weeks of supplementation with label dosing of Biocidin liquid on oral biofilms as assessed by SimplyPERIO (Spectrum Solutions, Salt Lake City, UT).

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 6, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 13, 2026

Completed
4 days until next milestone

Study Start

First participant enrolled

February 17, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2026

Completed
Last Updated

March 11, 2026

Status Verified

March 1, 2026

Enrollment Period

1 month

First QC Date

February 6, 2026

Last Update Submit

March 9, 2026

Conditions

Biofilm

Outcome Measures

Primary Outcomes (1)

  • Oral Biofilm Microorganisms

    SimplyPERIO - Oral biofilm microorganism test results are categorized as "low", "medium", and "high".

    Measured at baseline and conclusion of 2-week study

Study Arms (1)

Biocidin Liquid

EXPERIMENTAL

Broad-spectrum botanical liquid formula

Dietary Supplement: Biocidin Liquid

Interventions

Biocidin LiquidDIETARY_SUPPLEMENT

Broad-spectrum botanical liquid formula

Biocidin Liquid

Eligibility Criteria

Age25 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult females or males age ≥ 25 years
  • Ability to read and speak English
  • Willingness to take use oral Biocidin as directed for two weeks
  • Willingness not to change any other oral health practices for two weeks
  • Willingness not to change dietary habits for two weeks
  • Willingness to perform a SimplyPERIO oral microbiome test before and after the two-week Biocidin intervention

You may not qualify if:

  • Current use of oral Biocidin or botanical mouthwash
  • Use of antibiotics within the past 30 days
  • Current use of fixed intraoral orthodontic appliances (e.g., dental braces, fixed retainers, or similar devices)
  • Known allergies to any of the ingredients in the product
  • Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks
  • Participants unable to provide consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

OvationLab

Richmond, Virginia, 23220, United States

RECRUITING

Central Study Contacts

Chris D'Adamo, Ph.D.

CONTACT

‪(240) 232-2103‬chris@ovationlab.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 6, 2026

First Posted

February 13, 2026

Study Start

February 17, 2026

Primary Completion

April 1, 2026

Study Completion

April 1, 2026

Last Updated

March 11, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

IPD will be made available on a public repository

Time Frame
IPD will be made available indefinitely following analysis
Access Criteria
IPD will be available upon reasonable request

Locations

US(1)