Evaluation of the Postoperative Efficacy of Bilateral Lumbar Erector Spinae Plane Block (ESPB) in Patients Undergoing Lumbar Disc Herniation Repair Surgery

NCT07403734 | Active Not Recruiting

• 1 other identifier: BSH-ANES-MTK-01
• Study Type: observational
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate the efficacy of bilateral lumbar erector spinae plane (ESP) block in providing effective postoperative analgesia and its potential impact on early mobilization and length of hospital stay in patients undergoing surgical repair of lumbar disc herniation. Regional anesthesia techniques, particularly erector spinae plane blocks, have become an integral component of multimodal analgesia strategies in postoperative pain management. The ESP block has demonstrated effective analgesia across a wide spectrum of thoracic and abdominal surgeries and is increasingly utilized due to its ease of application and safety profile. By implementing multimodal analgesic techniques, this study seeks to achieve effective pain control, reduce opioid consumption and associated complications, facilitate early mobilization, decrease hospital length of stay, and enhance patient comfort.

Conditions

Opioid Consumption, Postoperative; ESPB; Postoperative Pain; Plane Blocks; Lumbar Disc Herniation; Hospital Stay Time; Patient Satisfaction

Keywords

lumbar erector spinae plane block; postoperative pain; espb; lumbar disc hernia repair surgery

Outcome Measures

Primary Outcomes (1)

• Change in Postoperative Pain Scores Using Numeric Rating Scale (NRS)

  Pain intensity will be measured using the 11-point Numeric Rating Scale (NRS: 0-10), where 0 represents "no pain" and 10 represents "worst pain imaginable." Pain scores will be assessed in three conditions: at rest, during deep breathing, and during coughing. The primary analysis will focus on pain scores at rest during the first 24 hours postoperatively.

  Assessed at 0, 15, 30, 60 minutes in the recovery unit and at 2, 6, 12, and 24 hours postoperatively on the ward (total assessment period: 24 hours)

Secondary Outcomes (9)

• Total Opioid (Tramadol) Consumption

  24 hours postoperatively

• Time to First Analgesic Request

  From recovery unit arrival (0 minutes) up to 24 hours postoperatively

• Number of Analgesic Demands

  24 hours postoperatively

• Need for Rescue Analgesia

  24 hours postoperatively

• Incidence and Severity of Postoperative Nausea and Vomiting (PONV)

  24 hours postoperatively

Study Arms (2)

ESP Block Group

Patients undergoing single-level lumbar disc herniation repair surgery who receive bilateral lumbar erector spinae plane block with 0.25% bupivacaine (20 ml per side, total 40 ml) under ultrasound guidance 30 minutes prior to anesthesia induction, in addition to standardized general anesthesia and postoperative patient-controlled analgesia.

Control Group (No Block)

Patients undergoing single-level lumbar disc herniation repair surgery who receive standardized general anesthesia and postoperative patient-controlled analgesia without erector spinae plane block.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18-70 years with single-level lumbar disc herniation scheduled for surgical repair at Başakşehir Çam and Sakura City Hospital, Department of Neurosurgery. Participants must be ASA I-III, able to provide informed consent, and capable of cooperating with postoperative assessments. Patients with previous lumbar surgery, chronic pain, contraindications to regional anesthesia, or significant comorbidities will be excluded.

You may qualify if:

• Male and female patients
• Age 18-70 years
• Patients scheduled to undergo single-level lumbar disc herniation repair surgery
• American Society of Anesthesiologists (ASA) physical status classification I, II, or III
• Willing to participate in the study (voluntary participation)
• Fully oriented and able to cooperate with study procedures

You may not qualify if:

• ASA physical status classification \> III
• Patients who refuse to participate in the study
• Age \< 18 years or \> 70 years
• Active infection at the site of block procedure
• Previous lumbar disc herniation surgery
• Chronic pain condition with continuous analgesic use
• Coagulopathy or bleeding disorders
• Patients unable to cooperate with postoperative pain assessments
• Known allergy to local anesthetic agents
• Body Mass Index (BMI) \> 35 kg/m²
• Renal insufficiency
• Hepatic insufficiency

Sponsors & Collaborators

• Başakşehir Çam & Sakura City Hospital: lead

Study Sites (1)

Başakşehir Çam Ve Sakura Şehir Hastanesi

Istanbul, Turkey (Türkiye)

Location

Related Publications (3)

• Koplewicz HS. From the Editor-in-Chief's Desk. J Child Adolesc Psychopharmacol. 2018 Jun;28(5):297. doi: 10.1089/cap.2018.29149.hsk. No abstract available.

  PMID: 29889567 RESULT

• Ivanusic J, Konishi Y, Barrington MJ. A Cadaveric Study Investigating the Mechanism of Action of Erector Spinae Blockade. Reg Anesth Pain Med. 2018 Aug;43(6):567-571. doi: 10.1097/AAP.0000000000000789.

  PMID: 29746445 RESULT

• Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.

  PMID: 27501016 RESULT

MeSH Terms

Conditions

Pain, Postoperative; Intervertebral Disc Displacement; Patient Satisfaction

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms; Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Hernia; Pathological Conditions, Anatomical; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor Doctor

Study Record Dates

• First Submitted: February 4, 2026
• First Posted: February 11, 2026
• Study Start: July 1, 2024
• Primary Completion: January 1, 2025
• Study Completion: March 1, 2026
• Last Updated: February 11, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)