Effect of Blink-Based Training on Cancer Detection in Colorectal Polyp Images by Medical Students/Non GI-trainees

NCT07401004 | Completed

• 1 other identifier: 25311_Blink
• Study Type: interventional
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates whether a brief educational intervention using Blink features can improve medical students' and non-GI trainees' ability to detect colorectal cancer in static polyp images. Secondary aims include evaluating changes in specificity, confidence, and interobserver agreement, determining which Blink features support accurate detection, and examining the link between the number of features recognized and diagnostic performance. The study will recruit medical students and non-GI trainees without prior training in polyp morphology or endoscopic image interpretation, who will complete an online pre- and post-intervention image-based survey.

Conditions

Colorectal Neoplasms; Colorectal Polyps

Keywords

Blink; Colorectal Polyps; Optical Diagnosis

Outcome Measures

Primary Outcomes (1)

• Change in sensitivity for detection of colorectal cancer in polyp images

  Sensitivity will be calculated as the proportion of correctly identified cancerous polyps out of all cancerous polyps presented. Comparison will be made between pre-intervention and post-intervention assessments.

  Immediately before and after the educational intervention (within one online survey session, approximately 15-20 minutes).

Secondary Outcomes (5)

• Change in specificity for cancer detection

  Immediately before and after the educational intervention (single online session, ~15-20 minutes).

• Change in self-reported diagnostic confidence

  Immediately before and after the educational intervention (same session).

• Change in interobserver agreement (Fleiss' kappa)

  Immediately before and after the educational intervention (same session).

• Correlation between presence of individual Blink features and correct cancer classification

  Baseline (pre-intervention) and immediately after the educational intervention (within the same online survey session, ~15-20 minutes).

• Correlation between number of Blink features identified and diagnostic accuracy

  Immediately after the educational intervention (within the same online survey session, ~15-20 minutes).

Study Arms (1)

Single Arm: Blink Features Training

EXPERIMENTAL

Medical students and non-GI trainees complete a baseline assessment of colorectal polyp images, receive a brief 2-minute educational video on Blink features, and then complete a post-intervention assessment.

Behavioral: Blink Features Training Video

Interventions

Blink Features Training Video BEHAVIORAL

A brief (2-minute) educational video introducing six Blink features (fold deformation, extra redness, chicken skin mucosa, depression, spontaneous bleeding, ulceration) to improve recognition of colorectal cancer in large non-pedunculated colorectal polyps.

Single Arm: Blink Features Training

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Images of large non-pedunculated colorectal polyps (LNPCPs) obtained from patients who have provided informed consent for the anonymous use of polyp images during colonoscopy (EC-2024-200).
• Medical students and non-GI trainees who have provided written informed consent to participate in the study.

You may not qualify if:

• Participants (students or non-GI trainees) with prior experience in endoscopy or polyp detection, or those who do not provide informed consent.
• Images deemed to be of insufficient quality by the principal investigator.
• Patients who do not provide informed consent for image use and data collection.

Sponsors & Collaborators

• Universitair Ziekenhuis Brussel: lead

Study Sites (1)

UZ Brussel

Jette, Brussels Capital, 1090, Belgium

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Gastroenterology trainee (Arts specialist in opleiding)

Model Details: Single group of medical students/non-GI trainee's will complete a pre-intervention assessment of colorectal polyp images, receive a brief educational intervention (2-minute Blink features video), and then complete a post-intervention assessment using the same images again.

Study Record Dates

• First Submitted: September 8, 2025
• First Posted: February 10, 2026
• Study Start: December 20, 2025
• Primary Completion: January 27, 2026
• Study Completion: January 27, 2026
• Last Updated: February 10, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP
• Time Frame: De-identified IPD and supporting information will be available starting 6 months after publication of the primary results and will remain available for 5 years.
• Access Criteria: Data will be shared with qualified researchers upon reasonable request and after signing a data access agreement.

Locations

BE (1)