Effect of Adding Dexamethasone to Bupivacaine in Ultrasound-Guided Supraclavicular Brachial Plexus Blocks Versus Bupivacaine Alone for Upper Limb Orthopaedic Surgery

NCT07399691 | Completed

• 1 other identifier: No-A/CHS/RC/19/2023
• Study Type: observational
• Target: 54
• Locations: 1 country
• Sites: 1

Brief Summary

• SCBPBs provides optimal conditions for procedures performed below the mid-upper arm (elbow, forearm, wrist, hand) due to its high success rate and ease of access.
• Dexamethasone, when administered perineurally as an adjuvant for a supraclavicular block, demonstrated early onset of sensory and motor block, a prolonged duration of sensory and motor block, and a lower number of rescue analgesics as compared to bupivacaine alone.
• A combination of dexamethasone and bupivacaine is paramount in adult orthopeadic patient to enhance the efficacy of pain management under ultrasound-guided supraclavicular brachial plexus block.

Conditions

Dexamethasone; Bupivacaine; Upper Limb Surgery

Keywords

dexamethasone,Bupivacaine,Analgesia,supraclavicular block

Outcome Measures

Primary Outcomes (1)

• The onset of sensory and motor blockade, and the duration of sensory and motor blockade in minutes.

  1. The onset of sensory: the period between injecting a study solution and losing sensation to a pinprick at every nerve distribution 2. The onset of motor block: The duration between the injection of the study solution and paresis in every nerve distribution. 3. duration of sensory: the period between the onset of a sensory block and the complete restoration of sensation. 4. Duration of motor block: the period between the onset of a motor block and the complete restoration of motor function.

  with in the first 24hrs after procedure

Secondary Outcomes (2)

• postoperative pain score by a visual analogue scale

  with in the first 24 hrs after procedure

• First analgesic request time

  With in the first 24 hrs after surgery

Study Arms (2)

Group DB

Patients received a supraclavicular brachial plexus block with dexamethasone 2 ml (8 mg) added to 38 ml of 0.25 % bupivacaine.

Drug: Dexamethasone 8 mg

Group B

Patients received a supraclavicular brachial plexus block with 40 ml of 0.25 % bupivacaine alone.

Interventions

Dexamethasone 8 mg DRUG

Adding 8 mg of dexamethasone to bupivacaine for ultrasound-guided supraclavicular block

Group DB

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study included 54 patients aged 18-60 years with ASA I and II who were scheduled for elective elbow, forearm, or hand surgery under ultrasound-guided supraclavicular bloc

You may qualify if:

• Aged 18-60 years with ASA I and II who were scheduled for elective elbow, forearm, or hand surgery under ultrasound-guided supraclavicular block.

You may not qualify if:

• Patients who refused, used local anaesthetics other than bupivacaine, had multiple traumas, addition of another additive, bleeding disorders, patients diagnosed with chronic pain, cancer pain, local infection at the injection site, history of local anaesthetic allergy, patients with anxiety, and inability to comprehend or use the pain rating scale

Sponsors & Collaborators

• Arsi University: lead

Study Sites (1)

Mohammed Gebi

Āsela, Ethiopia

Location

MeSH Terms

Interventions

Dexamethasone

Intervention Hierarchy (Ancestors)

Pregnadienetriols; Pregnadienes; Pregnanes; Steroids; Fused-Ring Compounds; Polycyclic Compounds; Steroids, Fluorinated

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer at arsi university

Study Record Dates

• First Submitted: January 23, 2026
• First Posted: February 10, 2026
• Study Start: January 1, 2024
• Primary Completion: April 30, 2024
• Study Completion: April 30, 2024
• Last Updated: February 10, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

ET (1)