Effect of Dexamethasone Adjuvant in Combined Supraclavicular Block and Suprascapular Block Versus Interscalene Block in Patients Undergoing Shoulder Arthroscopy

NCT06262893 | Recruiting

• 1 other identifier: Shoulder nerve blocks
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

In this study the investigators aim to compare the effect of the suprascapular- supraclavicular nerve block in association with dexamethasone to that of the interscalene brachial plexus block on analgesic effect during arthroscopic shoulder surgery, as postoperative pain scores ,postoperative consumption of analgesic rescue medications and diaphragmatic excursion assessment.

Conditions

Shoulder Arthroscopy Blocks; Dexamethasone

Outcome Measures

Primary Outcomes (1)

• Postoperative analgesia by visual analog scale (VAS).

  The primary outcome of this study will be to evaluate and compare between suprascapular-supraclavicular nerve block in association with dexamethasone to that of the interscalene brachial plexus block on postoperative analgesia by vas score during 48h postoperatively ( 2h , 6h , 12h, 24h and 48h). The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be').

  48 hours

Secondary Outcomes (1)

• Diaphragmatic excursion

  1hour postoperatively

Study Arms (2)

Interscalene block in shoulder arthroscopy

ACTIVE COMPARATOR

Procedure: Shoulder arthroscopy blocks

Combined Supraclavicular block and suprascapular block in shoulder arthroscopy

ACTIVE COMPARATOR

Procedure: Shoulder arthroscopy blocks

Interventions

Shoulder arthroscopy blocks PROCEDURE

Effect of dexamethasone adjuvant in combined supraclavicular block and suprascapular block versus Interscalene block in patients undergoing shoulder arthroscopy.

Combined Supraclavicular block and suprascapular block in shoulder arthroscopy; Interscalene block in shoulder arthroscopy

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ASA status 1,2.
• Age 18 years or older
• Elective shoulder arthroscopic surgery under general anesthesia and nerve block performed preoperatively.

You may not qualify if:

• Patient refusal
• Serious cardiac arrhythmias (including atrial fibrillation) or unstable coronary artery disease.
• Use of drugs that act on the autonomic nervous system (including β- blockers).
• Coagulation disorders..
• Anatomical disorders and/or neuropathic disease.
• BMI above 40.
• History of substance abuse.
• Chronic use of psychotropic and/or opioid.
• History of psychiatric diseases needing treatment.
• Allergy to any drug in the study protocol.
• Failure of nerve block performed in the preoperative block room when tested prior to entering the operating room (i.e. lack of loss of sensation to ice at the shoulder incision level).

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University

Asyut, Egypt

RECRUITING

Central Study Contacts

Mohamed Ahmed

CONTACT

01151994269; mohamedelkhatib90@gmail.com

Mohamed Talaat

CONTACT

+20 106 201 2031

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 26, 2023
• First Posted: February 16, 2024
• Study Start: February 25, 2024
• Primary Completion: December 1, 2025
• Study Completion: January 1, 2026
• Last Updated: April 22, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)