Effects of Powerlifting-Based Training in Athletes

NCT07398248 | Completed

• 1 other identifier: E-31679287-663.05-523405
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 2

Brief Summary

This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. The training program will be implemented for a specific period, and relevant blood parameters will be evaluated before and after the intervention. The findings of this study may contribute to a better understanding of the physiological effects of weightlifting-based training on athletes.

Conditions

Physical Fitness; Hormonal Response; Metabolic Parameters

Keywords

Powerlifting; Strength Training; Basketball

Outcome Measures

Primary Outcomes (6)

• Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL)

  Mean difference between baseline and post-intervention fasting serum total testosterone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  Baseline and post-intervention (8 weeks)

• Mean Change in Fasting Serum Cortisol Concentration Measured by ELISA (µg/dL)

  Mean difference between baseline and post-intervention fasting serum cortisol concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  Baseline and post-intervention (8 weeks)

• Mean Change in Fasting Serum Growth Hormone Concentration Measured by ELISA (ng/mL)

  Mean difference between baseline and post-intervention fasting serum growth hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  Baseline and post-intervention (8 weeks)

• Mean Change in Fasting Serum Thyroid-Stimulating Hormone Concentration Measured by ELISA (µIU/mL)

  Mean difference between baseline and post-intervention fasting serum thyroid-stimulating hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  Baseline and post-intervention (8 weeks)

• Mean Change in Fasting Serum Triiodothyronine Concentration Measured by ELISA (ng/dL)

  Mean difference between baseline and post-intervention fasting serum triiodothyronine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  Baseline and post-intervention (8 weeks)

• Mean Change in Fasting Serum Thyroxine Concentration Measured by ELISA (µg/dL)

  Mean difference between baseline and post-intervention fasting serum thyroxine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  Baseline and post-intervention (8 weeks)

Secondary Outcomes (6)

• Mean Change in Fasting Serum Insulin Concentration Measured by ELISA (µIU/mL)

  Baseline and post-intervention (8 weeks)

• Mean Change in Fasting Blood Glucose Concentration Measured by Automated Biochemical Analyzer (mg/dL)

  Baseline and post-intervention (8 weeks)

• Mean Change in Total Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)

  Baseline and post-intervention (8 weeks)

• Mean Change in Low-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)

  Baseline and post-intervention (8 weeks)

• Mean Change in High-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)

  Baseline and post-intervention (8 weeks)

Study Arms (2)

Powerlifting-Based Training Group

EXPERIMENTAL

Participants performed a structured powerlifting-based training program in addition to their regular basketball training. The intervention was conducted three days per week for six weeks. Each session lasted approximately 60 minutes and included a standardized warm-up, a powerlifting-focused main training phase, and a cool-down period. The training program emphasized the squat, bench press, and deadlift exercises performed with progressive intensity. Accessory exercises targeting lower-body strength, upper-body musculature, and core stability were included. High-intensity bodyweight exercises were also performed to enhance anaerobic capacity and neuromuscular performance. All training sessions were supervised by qualified staff.

Other: Powerlifting-Based Training; Other: Blood Sampling and Laboratory Analysis

Control Group

OTHER

Participants continued their usual basketball training routines throughout the study period without any additional strength or powerlifting-based exercises.

Other: Usual Basketball Training; Other: Blood Sampling and Laboratory Analysis

Interventions

Powerlifting-Based Training OTHER

Participants will perform a structured powerlifting-based training program including squat, bench press, and deadlift exercises, conducted 3 sessions per week for 8 weeks under supervision.

Powerlifting-Based Training Group

Usual Basketball Training OTHER

Participants continued their usual basketball training routines without any additional strength or powerlifting-based exercises.

Control Group

Blood Sampling and Laboratory Analysis OTHER

Venous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer.

Control Group; Powerlifting-Based Training Group

Eligibility Criteria

• Age: 18 Years - 24 Years
• Gender Eligibility Details: Only male athletes were eligible to participate in this study.
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male basketball players aged 18 to 24 years
• At least two years of regular sports experience
• Actively participating in basketball training and competition
• Voluntary participation with written informed consent

You may not qualify if:

• History of musculoskeletal injury or surgery within the last six months
• Presence of chronic disease or metabolic disorder
• Use of performance-enhancing drugs or hormonal supplements
• Participation in another structured training program during the study period

Sponsors & Collaborators

• Ramazan Erdoğan: lead

Study Sites (2)

Faculty of Sport Sciences

Tunceli, Center, 62000, Turkey (Türkiye)

Location

Munzur University

Bitlis, Tunceli, 62000, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Blood Specimen Collection

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: December 29, 2025
• First Posted: February 9, 2026
• Study Start: January 10, 2025
• Primary Completion: June 15, 2025
• Study Completion: October 15, 2025
• Last Updated: February 9, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (2)