NCT07396350

Brief Summary

Forty patients will be selected from the outpatient's clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable tooth in posterior mandibular area with immediate implants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2025

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2026

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 2, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 9, 2026

Completed
Last Updated

February 9, 2026

Status Verified

February 1, 2026

Enrollment Period

1 year

First QC Date

February 2, 2026

Last Update Submit

February 2, 2026

Conditions

Tooth Extraction

Keywords

dental implant

Outcome Measures

Primary Outcomes (1)

  • Implant stability

    The implant stability was evaluated immediately postoperatively and after 3, 6, and 12 months. An Osstell Mentor device (Osstell, Savadaled, Sweden; Integration Diagnostics) was utilized to assess implant stability utilizing resonance frequency analysis (RFA). Measurements were made at 90° in four different directions in order to calculate the RFA value. The implant stability quotient (ISQ) was calculated by averaging the results for each implant.

    12 months

Study Arms (2)

immediate implant with dentin-derived membrane

EXPERIMENTAL
Procedure: immediate implant with dentin-derived barrier membrane

immediate implant with extended platelet rich fibrin membrane

EXPERIMENTAL
Procedure: immediate implant with eprf membrane

Interventions

immediate implant with dentin-derived barrier membranePROCEDURE

immediate implant with dentin-derived barrier membrane with allograft covering any peri-implant defect and jumping gap.

immediate implant with dentin-derived membrane
immediate implant with eprf membranePROCEDURE

immediate implant with eprf membrane with allograft covering any peri-implant defect and jumping gap.

immediate implant with extended platelet rich fibrin membrane

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may not qualify if:

  • Tobacco Smokers.
  • Pregnancy.
  • Patients with a history of radiation to the head and neck.
  • Bruxism and parafunctional habits

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mansoura university

Al Mansurah, 002, Egypt

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 2, 2026

First Posted

February 9, 2026

Study Start

January 1, 2024

Primary Completion

January 1, 2025

Study Completion

January 1, 2026

Last Updated

February 9, 2026

Record last verified: 2026-02

Locations

EG(1)