NCT07387887

Brief Summary

This pilot study investigates the feasibility of objectively quantifying movement amplitude and amplitude decay during large-amplitude exercises using RGB camera-based video analysis in healthy volunteers. Six large-amplitude exercises are recorded across repeated trials, with the first repetition clinically confirmed as the individual's maximum reference. Movement amplitude is quantified using pose-based kinematic measures and complemented by an exploratory self-supervised visual transformer approach to characterize repetition-wise changes relative to the reference execution. The study aims to determine whether camera-based methods can detect amplitude decay patterns and identify moments requiring clinical verbal cues, thereby supporting future objective monitoring and feedback in large-amplitude exercise training.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 23, 2026

Completed
7 days until next milestone

Study Start

First participant enrolled

January 30, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 4, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2026

Completed
Last Updated

February 4, 2026

Status Verified

January 1, 2026

Enrollment Period

3 months

First QC Date

January 23, 2026

Last Update Submit

January 30, 2026

Conditions

Keywords

ExerciseMotion AnalysisVideo-recordingartificial intelligence

Outcome Measures

Primary Outcomes (1)

  • Change in Movement Amplitude Across Repetitions

    Movement amplitude will be quantified for each repetition of six large-amplitude exercises using normalized, RGB camera-based pose estimation. Amplitude decay will be defined as the change in movement amplitude across repeated executions within each exercise, reflecting repetition-related reduction in movement scali

    Baseline

Secondary Outcomes (3)

  • Reference-Based Visual Similarity Score

    Baseline

  • Repetition-Wise Amplitude Decay Trend

    Baseline

  • Association Between Kinematic Amplitude and Visual Representation Measures

    Baseline

Study Arms (1)

Healthy Volunteers - Observational Arm

EXPERIMENTAL

No Intervention / Observational: All participants are healthy adult volunteers who perform standardized large-amplitude exercises while being video recorded. No therapeutic intervention, randomization, or group allocation is applied. All participants undergo the same exercise protocol and data collection procedures.

Other: Large-Amplitude Exercise Observation and Video Recording

Interventions

Participants perform six standardized large-amplitude exercises (Floor-to-Ceiling Reach, Forward Step, Side Step, Sit-to-Stand, Forward Reach to Grasp and Release an Object, and Big Walking). Each exercise is repeated eight times while full-body movement is recorded using an RGB camera. The first repetition of each exercise is clinically confirmed as the participant's maximum movement amplitude and used as a reference for subsequent observational analysis. No therapeutic manipulation or feedback is provided beyond standard verbal confirmation.

Healthy Volunteers - Observational Arm

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Ability to stand, walk, reach, step, and perform sit-to-stand movements independently without assistance.
  • No self-reported or clinically diagnosed neurological, musculoskeletal, or vestibular disorders.
  • Normal or corrected-to-normal vision sufficient to follow visual instructions.

You may not qualify if:

  • History of neurological disorders (e.g., Parkinson's disease, stroke, multiple sclerosis, traumatic brain injury).
  • History of major musculoskeletal injury or surgery affecting upper or lower extremities that limits movement.
  • Presence of balance disorders or vestibular dysfunction.
  • Cardiovascular, respiratory, or metabolic conditions that may limit safe participation in physical exercise.
  • Current pain, dizziness, or excessive fatigue during movement or exercise.
  • Pregnancy or any condition for which moderate-intensity physical activity is contraindicated.
  • Use of assistive devices for walking or balance.
  • Refusal or inability to provide consent for RGB video recording.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Central Study Contacts

Güzin Kaya Aytutuldu

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Masking Details
This study employs single-level masking at the participant level. Participants are blinded to the specific analytical objectives and outcome measures of the study. While participants are informed that their movements are being video recorded during large-amplitude exercises, they are not informed about the criteria used to evaluate movement amplitude, repetition-wise changes, or the reference-based analysis approach.
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Model Details: The proposed model is designed to characterize movement scaling during large-amplitude exercises using RGB video recordings. It combines markerless pose-based kinematic analysis with an exploratory data-driven visual representation approach to quantify repetition-wise changes in movement execution relative to an individualized reference.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

January 23, 2026

First Posted

February 4, 2026

Study Start

January 30, 2026

Primary Completion

April 30, 2026

Study Completion

May 30, 2026

Last Updated

February 4, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share