Contextualization and Digitalization of WHO's Mental Health Action Gap Intervention Guide Substance Use Disorders Module

NCT07386574 | Recruiting

• 2 other identifiers: mhGAP-IG-SUD-00116645
• Study Type: interventional
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of study is to:

1. 1.To contextualize, adapt, customize and digitalize WHO's Mental Health Gap Action Programme Intervention Guide (e-mhGAP-IG); Substance Use Disorders Module (SUD module) V 2.0 for primary care settings (PCPs) in Pakistan.
2. 2.To test the feasibility and acceotability of the e-mhGAP-IG (SUD module) training program in a feasibility cluster randomized controlled (cRCT) trial to enable mental health services in primary health care settings in Pakistan.

Conditions

Substance Use Disorder (SUD)

Outcome Measures

Primary Outcomes (1)

• Feasibility measures

  Feasibility will be determined by recruitment and retention rates of participants throughout the study.

  From enrollement to the end of intervention at 4 weeks

Study Arms (2)

e-mhGAP-IG-SUD Intervention Group

EXPERIMENTAL

Participants randomized to this arm will receive a total of eight bi-weekly training sessions on the use of the adapted e-mhGAP-IG-SUD-Urdu mobile application. Training will focus on improving screening, diagnosis, and management of young people with SUD and referral to specialized services where needed.

Other: mhGap IG SUD Module Intervention Training

Control Group

ACTIVE COMPARATOR

Participants randomized to this arm will continue with routine practices and standard care for SUD management as currently being delivered.

Other: Control

Interventions

mhGap IG SUD Module Intervention Training OTHER

8 bi-weekly training sessions of e-mhGAP IG SUD Module

e-mhGAP-IG-SUD Intervention Group

Control OTHER

Routine practices or standard of care

Control Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Primary and non-specialized healthcare providers working in the identified health facilities for this study across three targeted cities; willing to give informed consent for participation in this trial.

You may not qualify if:

• Any primary and non-specialized healthcare provider who is not permanently working in the selected health facilities, has no access to a smart mobile phone and/or internet connection; and is uncomfortable using a mobile phone.

Sponsors & Collaborators

• Pakistan Institute of Living and Learning: lead
• Capaital University of Sceince of Technology: collaborator

Study Sites (1)

Basic Health Unit

Karachi, Pakistan

RECRUITING

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Central Study Contacts

Dr Ishrat Yousaf

CONTACT

+92 336 5289293; ishrat.yousaf@cust.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 19, 2026
• First Posted: February 4, 2026
• Study Start: January 1, 2025
• Primary Completion: March 15, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: May 1, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)