NCT07371195

Brief Summary

Upper cervical spine mobility plays a crucial role in temporomandibular joint (TMJ) function. This observational study investigates the relationship between upper cervical spine mobility and TMJ range of motion in patients diagnosed with temporomandibular disorders (TMD). Cervical hypomobility may restrict mandibular movement and contribute to TMJ dysfunction through shared biomechanical and neuromuscular mechanisms.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
4mo left

Started Feb 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress45%
Feb 2026Sep 2026

First Submitted

Initial submission to the registry

January 19, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 27, 2026

Completed
5 days until next milestone

Study Start

First participant enrolled

February 1, 2026

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Last Updated

January 27, 2026

Status Verified

January 1, 2026

Enrollment Period

6 months

First QC Date

January 19, 2026

Last Update Submit

January 19, 2026

Conditions

Keywords

Temporomandibular JointTemporomandibular DisordersUpper Cervical SpineCervical Mobility

Outcome Measures

Primary Outcomes (3)

  • Upper Cervical Spine Mobility

    Upper cervical spine mobility (flexion, extension, and left and right rotation) will be measured in degrees using a CROM device. Participants will be seated in an upright position, and each movement will be measured twice following standardized procedures. The mean value of both readings will be used for analysis.

    Single assessment session (baseline only)

  • Temporomandibular Joint Range of Motion (TMJ ROM)

    TMJ range of motion will be measured in millimetres using a standard ruler or digital calliper. Measurements include maximum mouth opening, lateral excursion (left and right), and protrusion. Each measurement will be taken twice, and the average will be recorded in millimetres to ensure reliability.

    Single assessment session (baseline only)

  • Correlation Between Upper Cervical Mobility and TMJ Range of Motion

    The relationship between upper cervical spine mobility (measured in degrees using the CROM device) and TMJ range of motion (measured in millimetres using a ruler or calliper) will be analysed statistically. Pearson or Spearman correlation coefficients will be applied, depending on data normality, to determine the strength and direction of association.

    Single assessment session (baseline only)

Study Arms (1)

Temporomandibular Disorder Group

Fifty patients with temporomandibular disorder will undergo evaluation of upper cervical spine mobility (flexion, extension, and rotation) and TMJ range of motion (opening, lateral excursion, and protrusion) using standardized instruments (CROM device and ruler/caliper).

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Participants will be adult patients (both male and female) aged 18 to 50 years who have been clinically diagnosed with temporomandibular joint (TMJ) dysfunction for more than three months. All participants will be recruited from the outpatient clinic of the Faculty of Physical Therapy, Deraya University, Minya, Egypt. Eligible participants will be medically stable and free from systemic or neurological disorders that could affect cervical or temporomandibular mobility.

You may qualify if:

  • Medically stable individuals who consent to participate in the study.
  • Age between 18 and 50 years.
  • Both male and female participants.
  • Patients diagnosed with temporomandibular joint (TMJ) dysfunction for at least three months.

You may not qualify if:

  • Presence of systemic diseases.
  • Body mass index (BMI) greater than 30 kg/m².
  • Pregnancy.
  • Recent physical therapy for cervical spine disorders, headaches, or temporomandibular dysfunction.
  • Cervical radiculopathy or other neurological disorders.
  • History of trauma or major psychological problems.
  • Generalized joint hypermobility.
  • Down syndrome.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

faculty of physical therapy, Deraya University

Minya, Menia Governorate, Egypt

Location

MeSH Terms

Conditions

Temporomandibular Joint DisordersTemporomandibular Joint Dysfunction SyndromePost-Traumatic Headache

Condition Hierarchy (Ancestors)

Craniomandibular DisordersMandibular DiseasesJaw DiseasesMusculoskeletal DiseasesJoint DiseasesMuscular DiseasesStomatognathic DiseasesMyofascial Pain SyndromesHeadache Disorders, SecondaryHeadache DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Central Study Contacts

Demiana Hany Habib

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 19, 2026

First Posted

January 27, 2026

Study Start

February 1, 2026

Primary Completion (Estimated)

August 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

January 27, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations