NCT07364721

Brief Summary

ABSTRACT Objective:This study aimed to compare the efficacy of central posteroanterior (PA) Maitland mobilization with myofascial release (MFR) and McKenzie prone press-up (PPU) exercise with MFR in the treatment of adult patients with chronic non-specific low back pain (CNLBP). Materials and Methods:A randomized controlled trial was conducted at Salhab Center and Al Shifa's Specialized Complex in Bethlehem between January 2023 and May 2024. The study included 50 adult patients (aged 18-50) with CNLBP of more than 3 months but less than 2 years' duration, referred by an orthopedic specialist at Beit Sahour Medical Center. Participants were randomly assigned to two groups: one received central PA Maitland mobilization with MFR, and the other received McKenzie PPU exercise with MFR. Pain intensity, functional impairment, and fear-avoidance beliefs were assessed using the Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and Fear-Avoidance Beliefs Questionnaire (FABQ). Each patient underwent three sessions per week for four weeks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2024

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

January 3, 2026

Completed
20 days until next milestone

First Posted

Study publicly available on registry

January 23, 2026

Completed
Last Updated

January 23, 2026

Status Verified

January 1, 2026

Enrollment Period

4 months

First QC Date

January 3, 2026

Last Update Submit

January 16, 2026

Conditions

Keywords

McKenzie ExerciseLow back painPosteroanterior mobilization

Outcome Measures

Primary Outcomes (1)

  • Oswestry Disability Index

    0% (no disability) to 100% (severe disability)

    4 WEEKS

Other Outcomes (2)

  • Visual Analogu Scale

    4 WEEKS

  • Fear-Avoidance Belief Questionnaire

    4 WEEKS

Study Arms (2)

Arm 1- Group A :Central PA Maitland mobilization with MFR

EXPERIMENTAL

Central PA Maitland mobilization with MFR

Other: Group B (McKenzie PPU exercise with MFR)Other: McKenzie PPU exercise with MFR

Arm 2- Group B:McKenzie PPU exercise with MFR

EXPERIMENTAL

Patient position: The patient assumes a prone position. investigator position: The investigator stands beside the patient and provides verbal instruction. Direction: Patients were being instructed to perform PPU exercise by using their upper limbs to push their upper body up into spinal extension while the pelvis remained on the treatment table. The patient is trained to extend the lumbar spine to the maximum pain-free range. Frequency: Ten repetitions for three sets with a 30-second break between each set for almost 10 minutes \[27\].

Other: Group B (McKenzie PPU exercise with MFR)Other: Central Posteroanterior Mobilization

Interventions

Patient position: The patient assumes a prone position. Therapist position: The therapist stands beside the patient and provides verbal instruction. Direction: Patients were being instructed to perform PPU exercise by using their upper limbs to push their upper body up into spinal extension while the pelvis remained on the treatment table. The patient is trained to extend the lumbar spine to the maximum pain-free range. Frequency: Ten repetitions for three sets with a 30-second break between each set for almost 10 minutes

Arm 1- Group A :Central PA Maitland mobilization with MFRArm 2- Group B:McKenzie PPU exercise with MFR

According to Maitland's concept, mobilization technique including passive accessory intervertebral movement was applied to cause movement in the stiff vertebral segment without the active involvement of the muscles \[44\]. Central PA mobilization technique is a cornerstone of Maitland vertebral mobilization \[38\]. It can be achieved by passive force onto a vertebral segment in the PA direction \[44\]. Patient position: When applying this technique, the patient assumes a relaxed and comfortable prone position, with the arms positioned alongside the body \[23, 24\]. investigator position: The investigator stands close to the patient, with their sternum perpendicular to the selected lumbar spinous process \[23\]. The investigator uses the ulnar surface of the hand (pisiform) over the selected spinous process in the lumbar spine, another hand taken was placed above the first hand to reinforce, and the elbow should slightly bent with forearm in neutral between supination \& pronation.

Arm 2- Group B:McKenzie PPU exercise with MFR

Patient position: The patient assumes a prone position. investigator position: The investigator stands beside the patient and provides verbal instruction. Direction: Patients were being instructed to perform PPU exercise by using their upper limbs to push their upper body up into spinal extension while the pelvis remained on the treatment table. The patient is trained to extend the lumbar spine to the maximum pain-free range. Frequency: Ten repetitions for three sets with a 30-second break between each set for almost 10 minutes

Arm 1- Group A :Central PA Maitland mobilization with MFR

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • and 50 years of age,
  • Male or female, with NSLBP localized between the lower rib and the gluteal fold
  • Persisting for more than three months and occurring on at least half of the days in the past three months, with pain affecting daily functional activities.
  • VAS score between 40 mm and 80 mm at the initial assessment
  • No use of NSAID medications during treatment sessions.

You may not qualify if:

  • Patients younger than 18 or older than 50 years,
  • Those with mental health disorders, systemic or neurological diseases, or specific spinal pathologies such as facet joint dysfunction, piriformis syndrome, disc herniation, spinal tumors, spondylitis, spondylolisthesis, spinal stenosis, or spinal osteoporosis. Patients were also excluded if they had contraindications to mobilization, a history of spinal surgery or epidural injections, physiotherapy for LBP within the last six months, a VAS score outside the 40-80 mm range, pregnancy, or a current upper limb injury.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Palestine Ahliya University

Bethlehem, West Bank, P150, Palestinian Territories

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: The treatment techniques applied to the two groups are as follows. Group A (Central PA Maitland mobilization with MFR): 25 patients received 3 sessions per week for 4 weeks; the central PA mobilization technique was applied for 10 minutes and MFR for 20 minutes (30 seconds break each five minutes). Group B (McKenzie PPU exercise with MFR): 25 patients received three sessions per week for four weeks, with each session consisting of 10 minutes of McKenzie PPU exercise followed by 20 minutes of MFR, also with a 30-second break every five minutes.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chairperson, Department of Medical Sciences - Master's

Study Record Dates

First Submitted

January 3, 2026

First Posted

January 23, 2026

Study Start

December 1, 2023

Primary Completion

April 1, 2024

Study Completion

May 1, 2024

Last Updated

January 23, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations