Trials Sponsors Conditions Drugs Pricing

Conditions

Satiety in Healthy Volunteers

Outcome Measures

Primary Outcomes (1)

Blood GLP-1 iAUC
Incremental area under the curve (iAUC) for GLP-1 from immediately prior to test-product consumption (t=0) to t=120 min following test-product consumption.
For 2 hours post intervention

Secondary Outcomes (3)

Blood PYY iAUC
For 2 hours post intervention
Gastric Emptying Rate/Transit Time via Acetaminophen
Oral dose of acetaminophen with blood samples taken for 2 hours post intervention
Change in Perceived Satiety Levels
For 2 hours post intervention

Study Arms (4)

Control Soda

PLACEBO COMPARATOR

Participants will consume one 12 oz can of a control soda

Other: Control Soda

Prebiotic Soda - Shelf Stable

EXPERIMENTAL

Participants will consume one 12 oz can of the shelf stable prebiotic soda

Other: Prebiotic Soda - Shelf Stable

Prebiotic Soda - Refrigerated

EXPERIMENTAL

Participants will consume one 12 oz can of the refrigerated prebiotic soda

Other: Prebiotic Soda - Refrigerated

Interventions

Control SodaOther

Participants will consume one 12 oz can of a control soda that contains 0 g dietary fiber and 4 g total sugar.

Control Soda

Prebiotic Soda - Shelf StableOther

Participants will consume one 12 oz can of a shelf stable prebiotic soda that contains 6 g dietary fiber and 4 g total sugar.

Prebiotic Soda - Shelf Stable

Eligibility Criteria

Age18 Years - 60 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Adults aged 18-60 years, inclusive.
BMI between 18.0 and 30.0 kg/m2.

Sponsors & Collaborators

Olipop, PBC
Industrylead
INQUIS Clinical Research
Industrycollaborator

Study Sites (1)

Inquis Clinical Research

Toronto, Ontario, M5C 2N8, Canada

MeSH Terms

Interventions

sodium bicarbonate-based toothpaste

Study Officials

Janice Campbell
INQUIS Clinical Research
STUDY DIRECTOR

Enrollment

15 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: SINGLE
Who Masked: PARTICIPANT
Purpose: BASIC SCIENCE
Intervention Model: CROSSOVER
Sponsor Type: INDUSTRY
Responsible Party: SPONSOR

Study Record Dates

First Submitted

January 9, 2026

First Posted

January 23, 2026

Study Start

February 2, 2026

Actual (reported)

Effect of Prebiotic Sodas on Postprandial Levels of GLP-1, PYY, Transit Time and Satiety Levels: A Pilot Study

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (4)

Control Soda

Prebiotic Soda - Shelf Stable

Prebiotic Soda - Refrigerated

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Study Officials

Enrollment

Study Design

Study Record Dates

Prebiotic Soda - Shelf Stable + Functional Ingredient

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (4)

Control Soda

Prebiotic Soda - Shelf Stable

Prebiotic Soda - Refrigerated

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Study Officials

Enrollment

Study Design

Study Record Dates

Prebiotic Soda - Shelf Stable + Functional Ingredient

You may not qualify if:

Data Sharing

Source record

Locations