Virtual Reality-Based Five-Repetition Sit-to-Stand Test in Young Adults

NCT07362368 | Not Yet Recruiting

• 1 other identifier: SelcukU_PT_VR5STS_ADAPTATION_1
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Lower extremity muscle strength is a fundamental determinant of an individual's ability to maintain functional mobility, preserve balance, and perform activities of daily living independently. One of the methods used for the comprehensive evaluation of these functions is the Five-Repetition Sit-to-Stand (5STS) test, which is considered an effective tool for assessing lower extremity strength, balance, and functional mobility in both healthy individuals and various clinical populations. In this test, participants are required to consecutively stand up from and sit down on a chair five times without using their arms, and the completion time is recorded in seconds to objectively evaluate functional capacity. Due to its simplicity, low cost, and high reliability, the 5STS test is widely used in clinical and research settings. However, functional tests administered in conventional clinical environments may be insufficiently standardized due to factors such as examiner-related variability, measurement errors, and environmental influences. This limitation makes it difficult to detect small performance differences and restricts test repeatability. In recent years, rapidly advancing virtual reality (VR) technology has contributed to overcoming these limitations by offering the potential to digitally standardize measurement processes. VR systems, which recreate real-life scenarios in a three-dimensional and interactive manner, allow for a more comprehensive and objective assessment of motor performance. In addition, by increasing user interaction and reducing observer-related errors, VR enhances clinical validity. One study has reported that the most important advantage of VR in clinical balance assessments is its ability to provide a fully controllable, repeatable, and standardized environment. Similarly, a systematic review found that VR-based exercises resulted in significant improvements in motor skills, balance, and cognitive function, while increasing user engagement and motivation and thereby contributing to more effective rehabilitation outcomes. Current literature indicates that VR technology is increasingly being utilized in physiotherapy and exercise sciences. In one study, the validity and feasibility of a VR adaptation of the Wingate Anaerobic Test were investigated, and it was reported that the VR version produced performance outcomes comparable to the conventional test, while participant satisfaction was significantly higher with the VR-based method. Likewise, another study demonstrated that the VR adaptation of the Six-Minute Pegboard and Ring Test exhibited high levels of validity and reliability. Together, these studies indicate that VR-based functional tests are both feasible and clinically consistent. Despite this, no studies to date have examined the validity and reliability of the Five-Repetition Sit-to-Stand test in an immersive VR environment for assessing lower extremity function. Therefore, the present study aims to determine the validity, reliability, and feasibility of a virtual reality-based Five-Repetition Sit-to-Stand test (5STS-VR) developed on the Meta Quest 3 platform in asymptomatic young adults. Additionally, convergent validity will be evaluated by analyzing the relationships between performance data obtained from the virtual environment and outcomes of the Y-Balance Test and lower extremity muscle strength measurements.

Conditions

Functional Mobility; Virtual Reality-Based Functional Assessment

Keywords

Functional Mobility; Five-Repetition Sit-to-Stand Test; Virtual Reality; Immersive Virtual Reality; Validity; Reliability; Young Adults

Outcome Measures

Primary Outcomes (1)

• Five-Repetition Sit-to-Stand Test - Virtual Reality (5STS-VR)

  This outcome measure will be used to assess lower extremity functional performance using an immersive virtual reality-based adaptation of the Five-Repetition Sit-to-Stand test. Test completion time will be automatically recorded by the system. Validity will be evaluated by comparison with the conventional Five-Repetition Sit-to-Stand test, and reliability will be assessed using repeated measurements performed one week apart.

  Baseline and 1-week follow-up

Secondary Outcomes (4)

• Five-Repetition Sit-to-Stand Test - Conventional

  Baseline

• Y-Balance Test

  Baseline

• Lower Extremity Muscle Strength

  Baseline

• Participant Satisfaction

  Baseline

Study Arms (1)

Asymptomatic Young Adults

Asymptomatic young adults aged 18-30 years undergoing conventional and immersive virtual reality-based Five-Repetition Sit-to-Stand assessments to evaluate feasibility, validity, and reliability.

Other: Clinical Assessments

Interventions

Clinical Assessments OTHER

Participants will perform the Five-Repetition Sit-to-Stand test using an immersive virtual reality application developed for the Meta Quest 3 platform. The virtual environment digitally replicates the conventional test setup, including chair height, starting position, movement sequence, and completion criteria. Test duration will be automatically recorded by the system. The virtual reality-based assessment is designed to provide a standardized, objective, and reproducible evaluation of lower extremity functional performance and will be repeated to assess test-retest reliability.

Asymptomatic Young Adults

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Asymptomatic young adults aged 18-30 years who are able to perform activities of daily living independently and have no neurological, cardiovascular, or musculoskeletal conditions affecting functional performance.

You may qualify if:

• Aged between 18 and 30 years,
• Asymptomatic, with no neurological, cardiovascular, or musculoskeletal symptoms,
• Ability to perform activities of daily living independently,
• Visual, auditory, and vestibular functions adequate for virtual reality applications,
• Ability to understand and follow instructions in Turkish,
• Willingness to participate voluntarily in the study.

You may not qualify if:

• History of lower extremity injury, surgical procedure, or serious musculoskeletal condition within the past six months,
• Presence of vestibular disorders, balance impairment, or visual or hearing impairments,
• Experiencing symptoms of VR sickness, such as dizziness, nausea, or spatial disorientation during virtual reality applications,
• Diagnosis of neurological, cardiovascular, or metabolic disease,
• Engaging in intensive exercise or being a professional athlete,
• Insufficient cognitive ability to understand test instructions,
• Voluntary withdrawal from the study during the research process.

Sponsors & Collaborators

• Selcuk University: lead

Study Sites (1)

Selcuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Konya, Selcuklu, 42130, Turkey (Türkiye)

Location

Related Publications (7)

• Maden C, Gozacan Karabulut D, Bagci B. Validity and reliability of an immersive virtual reality adaptation of the 6-minute pegboard and ring test. Hand Surg Rehabil. 2025 Feb;44(1):101981. doi: 10.1016/j.hansur.2024.101981. Epub 2024 Oct 30.

  PMID: 39486588 BACKGROUND

• Bayram GA, Sahin GE, Yilmaz G, Tayboga UI, Celik AG, Yildirim Y, Saribas PK, Tarakci D. Integration of the wingate anaerobic test into a virtual reality- based evaluation system. BMC Sports Sci Med Rehabil. 2025 Jul 2;17(1):163. doi: 10.1186/s13102-025-01220-4.

  PMID: 40605090 BACKGROUND

• Ali SG, Wang X, Li P, Jung Y, Bi L, Kim J, Chen Y, Feng DD, Magnenat Thalmann N, Wang J, Sheng B. A systematic review: Virtual-reality-based techniques for human exercises and health improvement. Front Public Health. 2023 Mar 23;11:1143947. doi: 10.3389/fpubh.2023.1143947. eCollection 2023.

  PMID: 37033028 BACKGROUND

• Morel M, Bideau B, Lardy J, Kulpa R. Advantages and limitations of virtual reality for balance assessment and rehabilitation. Neurophysiol Clin. 2015 Nov;45(4-5):315-26. doi: 10.1016/j.neucli.2015.09.007. Epub 2015 Oct 31.

  PMID: 26527045 BACKGROUND

• Scott H, Griffin C, Coggins W, Elberson B, Abdeldayem M, Virmani T, Larson-Prior LJ, Petersen E. Virtual Reality in the Neurosciences: Current Practice and Future Directions. Front Surg. 2022 Feb 18;8:807195. doi: 10.3389/fsurg.2021.807195. eCollection 2021.

  PMID: 35252318 BACKGROUND

• Rizzo AS, Koenig ST. Is clinical virtual reality ready for primetime? Neuropsychology. 2017 Nov;31(8):877-899. doi: 10.1037/neu0000405.

  PMID: 29376669 BACKGROUND

• Munoz-Bermejo L, Adsuar JC, Mendoza-Munoz M, Barrios-Fernandez S, Garcia-Gordillo MA, Perez-Gomez J, Carlos-Vivas J. Test-Retest Reliability of Five Times Sit to Stand Test (FTSST) in Adults: A Systematic Review and Meta-Analysis. Biology (Basel). 2021 Jun 9;10(6):510. doi: 10.3390/biology10060510.

  PMID: 34207604 BACKGROUND

Study Officials

• İsmail ÖZSOY, Assoc. Prof. Dr.

  Selcuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Konya, Türkiye

  STUDY CHAIR

• Yusuf ÖZBAĞ

  Selcuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Konya, Türkiye

  STUDY CHAIR

Central Study Contacts

Mehmet K ALTUNOK, PHD(c) in PT

CONTACT

5558175133; mehmetkaan.altunok@selcuk.edu.tr

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: January 15, 2026
• First Posted: January 23, 2026
• Study Start: February 2, 2026
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): July 30, 2026
• Last Updated: January 23, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)