Nurse-Led Staged Art Therapy Effects on Psychological Distress and Pregnancy Outcomes in AIH: RCT

NCT07356830 | Enrolling By Invitation

• 1 other identifier: KY-2025-193
• Study Type: interventional
• Target: 254
• Locations: 1 country
• Sites: 1

Brief Summary

Music therapy is a comprehensive therapy that integrates musicology, psychology and medicine. It is an application and development outside the field of traditional art appreciation and aesthetics . Clinical studies have shown that music therapy can improve the patient 's sense of tension, relieve anxiety, and has a certain effect of auxiliary analgesia. At the same time, music therapy is easy to operate, economical and feasible, non-invasive and safe , and improves physical and mental health. Music therapy can work through the hypothalamus-pituitary and other multi-system cross-activity, arouse the patient 's pleasant thoughts and emotional experience, and has the function of regulating psychology and physiology . Many studies at home and abroad have shown that most infertility patients have negative emotions, such as anxiety and depression For Chinese women, affected by the traditional culture of " no filial piety, no filial piety, no filial piety, " patients are under greater reproductive pressure. Many studies have confirmed that psychological stress can affect the function of the hypothalamus-pituitary-ovarian axis, inhibit the secretion of gonadotropins by the pituitary gland, interfere with follicular growth, affect the developmental potential of oocytes and embryos, and thus affect reproductive function . Psychological stress can also interfere with embryo implantation by inhibiting endometrial receptivity . Anxiety can promote sympathetic nerve excitation, release more catecholamines, hinder the growth of follicles in the ovary and the secretion of luteinizing hormone, and affect the clinical effect of superovulation. The decrease of estrogen and progesterone secretion affects the number and quality of follicles and the development of endometrium, thus reducing the pregnancy rate Long-term depression can also endanger physical health, destroy pregnancy outcomes, and lead to abortion. With the development of medicine, the ' biological-psychological-social ' medical model has been paid more and more attention, and the psychological factors in the treatment of infertility have also attracted more and more attention. Although the mechanism of music therapy is not yet clear, studies have shown that it can inhibit the secretion of endogenous hormones such as adrenaline.

Conditions

Music Therapy

Outcome Measures

Primary Outcomes (1)

• Pregnancy rate

  Pregnant was checked 14 days after the end of artificial insemination.

  Pregnant was checked 14 days after the end of artificial insemination.

Study Arms (2)

Experimental group : on the basis of the control group with music therapy.

EXPERIMENTAL

on the basis of the control group with music therapy.

Other: music therapy

The control group was given routine nursing care

NO INTERVENTION

In the control group, psychological nursing was supplemented in the process of routine diagnosis and treatment. The main contents are as follows : At the beginning of the filing date of husband 's artificial insemination, nurses carefully understood the basic situation of patients, including the living environment and educational background, and gave patients psychological counseling and care. At the same time, they carried out propaganda and education for patients, explained the treatment process and principle of artificial insemination, dispelled the fear caused by patients ' lack of understanding of treatment technology, eliminated patients ' anxiety, depression and other negative emotions, let patients unload their psychological burden as soon as possible, familiarize themselves with the diagnosis and treatment environment, and improve patients ' self-confidence by introducing successful cases. Promote their active treatment until the end of the entire husband 's artificial insemi

Interventions

music therapy OTHER

Experimental group : on the basis of the control group with music therapy.

Experimental group : on the basis of the control group with music therapy.

Eligibility Criteria

• Age: 18 Years - 40 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

Sponsors & Collaborators

• The Fourth Affiliated Hospital of Zhejiang University School of Medicine: lead

Study Sites (1)

The Fouth Affiliated Hospital of Zhejiang University School of Medicine

Yiwu, Zhejiang, 322000, China

Location

MeSH Terms

Interventions

Music Therapy

Intervention Hierarchy (Ancestors)

Sensory Art Therapies; Complementary Therapies; Therapeutics; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Psychotherapy; Behavioral Disciplines and Activities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 13, 2026
• First Posted: January 21, 2026
• Study Start: August 6, 2025
• Primary Completion: December 31, 2025
• Study Completion: March 31, 2026
• Last Updated: March 20, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will share

Locations

CN (1)