Impact of Haskap Berries on Recovery From High Intensity Resistance Training

NCT07344727 | Recruiting

• 1 other identifier: 2025-2138
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this clinical trial is to determine how certain food items affect oxidative stress, inflammation, and performance recovery from exercise induced muscle damage in a resistance trained population. The main questions The investigators aim to answer are the following:

• Do Haskaps speed the recovery of oxidative stress and inflammation markers after an intense lower body workout in resistance trained adults?
• Do Haskaps speed the recovery of performance measures after an intense lower body workout in resistance trained adults?
• The data collected in this investigation may also be used to ask additional questions not yet identified. For example, the investigators may use the stored samples to evaluate how the blood metabolites of participants differ before and after intense exercise. These additional questions are called secondary analyses. Please note that no genetic analysis will be conducted and racial and ethnic differences among participants will not be used in any secondary analyses. Researches will compare Haskap juice to a color, flavor and carbohydrate matched placebo to see if Haskaps speed recovery in inflammation, oxidative stress and performance.
• Participants will be asked to drink either Haskap juice or placebo and follow a low polyphenolic diet
• Participants will perform an intense resistance workout
• Participants will have their blood drawn before and after the workout
• Performance will be analyzed at 24, 48 and 72 hours after the workout

Conditions

Inflammation; Oxidative Stress; Resistance Exercise; Recovery; Exercise Performance Recovery

Keywords

exercise performance; resistance exercise; recovery; oxidative stress; inflammation

Outcome Measures

Primary Outcomes (8)

• Force Production

  Maximal Voluntary Contraction (MVC) to assess force production of knee extensors at 60 degrees.

  72 hours

• Barbell Velocity

  Barbell velocity will be measure to determine how squat velocity recovers over the course of the study.

  72 hours

• Vertical Jump

  Force plates will be used to evaluate vertical jump height.

  72 hours

• Inflammation (pg/mL)

  Serum interleukin (IL) IL-6, IL-10, IL-1ra, tumor necrosis factor alpha (TNF-alpha),

  11 days

• Lipid peroxidation

  Plasma Malondialdehyde (MDA)

  11 days

• Creatine Kinase

  Plasma

  11 days

• C-Reactive Protein

  Plasma

  11 days

• Protein Carbonyls

  Plasma

  11 days

Secondary Outcomes (3)

• Soreness

  72 hours

• Acute Diet

  9 days

• Sleep Questionnaire

  11 days

Study Arms (2)

Placebo Control

PLACEBO COMPARATOR

The placebo supplement will have no polyphenol content and will be carbohydrate-matched to the experimental group. A twice daily dose (10-12 hours apart) will be consumed for 11 days.

Dietary Supplement: Placebo Comparator

Haskap

EXPERIMENTAL

The haskap supplement will consist of a haskap berry smoothie. A twice daily dose (10-12) hours apart will be consumed for 11 days.

Dietary Supplement: Haskap berry smoothie

Interventions

Haskap berry smoothie DIETARY_SUPPLEMENT

A smoothie blend of berries and water

Haskap

Placebo Comparator DIETARY_SUPPLEMENT

A smoothie with no polyphenolic content and matched in carbohydrate composition to the experimental haskap smoothie

Placebo Control

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• + years of barbell squat experience
• Currently squatting at least once a week

You may not qualify if:

• BMI \<18 or \> 40 kg/m\^2
• potential allergy to Haskap or placebo ingredients
• anti-inflammatory, weight loss, anabolic steroids, testosterone, or other drugs that may interfere with the measures of the study or any other medications that may interfere with study measures
• pregnant or lactating woman
• diagnosis with type 1 or type 2 diabetes, hypo-/hyperthyroidism or any other condition that may interfere with study measures
• smoke cigarettes
• lower extremity injury within the last year
• currently following a special diet including vegan, vegetarian, low carbohydrate, or ketogenic.
• currently consuming any of the following products: tart cherry juice, pomegranate juice, or 1 or more cups of acai or other berries per day.

Sponsors & Collaborators

• Montana State University: lead
• Montana State Agricultural Experiment Station: collaborator

Study Sites (1)

Montana State University

Bozeman, Montana, 59715, United States

RECRUITING

MeSH Terms

Conditions

Inflammation

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Mary P Miles

  Montana State University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Bryce Peterson

CONTACT

40666975460; brycepeterson@montana.edu

Adrianna Yeats

CONTACT

3864516656; adriannayeats@montana.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Placebo and haskap interventions were designed to be comparable in taste, carbohydrate content, and appearance.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 7, 2026
• First Posted: January 15, 2026
• Study Start: October 21, 2025
• Primary Completion: March 1, 2026
• Study Completion: May 1, 2026
• Last Updated: January 21, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)