Turkish Validation of the Nijmegen Questionnaire in COPD

NCT07344649 | Recruiting

• 1 other identifier: Nijmegen&TR
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Dysfunctional breathing is a common and clinically relevant problem in patients with chronic obstructive pulmonary disease (COPD), contributing to increased dyspnea perception, reduced exercise tolerance, and impaired quality of life. The Nijmegen Questionnaire (NQ) is a widely used symptom-based instrument for screening dysfunctional breathing; however, a validated Turkish version for patients with COPD is currently unavailable. This observational methodological study aims to translate, culturally adapt, and evaluate the validity and reliability of the Turkish version of the Nijmegen Questionnaire (NQ-TR) in individuals with stable COPD.

Conditions

COPD

Outcome Measures

Primary Outcomes (1)

• Turkish version of the Nijmegen Questionnaire (NQ-TR)

  The Nijmegen Questionnaire is a validated self-report instrument used to assess symptoms related to dysfunctional breathing and hyperventilation. It consists of 16 items evaluating the frequency of respiratory and non-respiratory symptoms, with higher total scores indicating greater symptom severity. In this study, the Turkish-validated version of the Nijmegen Questionnaire (NQ-TR) will be used to evaluate dysfunctional breathing symptoms in participants.

  Baseline and 1 week

Secondary Outcomes (4)

• COPD Assessment Test (CAT)

  Baseline

• Modified Medical Research Council (mMRC) Dyspnea Scale

  Baseline

• Dyspnea-12 (D-12) Scale

  Baseline

• Hospital Anxiety and Depression Scale (HADS)

  Baseline

Study Arms (1)

COPD

Other: Questionnaires

Interventions

Questionnaires OTHER

Administration of validated self-reported questionnaires (Nijmegen Questionnaire, CAT, mMRC, HADS, Dyspnea-12)

COPD

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population consists of adults aged 18 years and older with a confirmed diagnosis of chronic obstructive pulmonary disease (COPD) according to GOLD criteria. Eligible participants are clinically stable patients attending the pulmonology outpatient clinic of a tertiary care hospital, with no acute exacerbation or hospitalization within the previous four weeks. All participants are Turkish-speaking, able to complete self-reported questionnaires, and provide written informed consent.

You may qualify if:

• Adults aged 18 years and older
• Diagnosis of COPD confirmed according to GOLD criteria
• Clinically stable disease (no acute exacerbation or hospitalization within the last 4 weeks)
• Ability to read and understand Turkish
• Willingness to participate and provide written informed consent

You may not qualify if:

• Acute COPD exacerbation or respiratory infection within the previous 4 weeks
• Presence of severe cardiac, neurological, or systemic disease affecting questionnaire responses
• Coexisting pulmonary conditions such as bronchiectasis, lung cancer, prior pulmonary tuberculosis, pleural disease, or history of lung surgery
• Moderate to severe cognitive impairment or communication difficulties
• Severe visual or hearing impairment preventing questionnaire completion
• Pregnancy
• Refusal to participate or withdrawal during the study

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead

Study Sites (1)

Esra Pehlivan

Istanbul, 34668, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Central Study Contacts

Esra Pehlivan

CONTACT

0 216 777 8 777; esra.pehlivan@sbu.edu.tr

Cahidenur Koçak

CONTACT

0 216 777 8 777; cahidekocak25@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 1, 2026
• First Posted: January 15, 2026
• Study Start: April 13, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): January 1, 2027
• Last Updated: April 15, 2026

Record last verified: 2026-04

Locations

TU (1)