NCT07342166

Brief Summary

This study is a double-blind randomized controlled trial aiming to investigate the effects of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 8, 2023

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 21, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 21, 2025

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

December 25, 2025

Completed
21 days until next milestone

First Posted

Study publicly available on registry

January 15, 2026

Completed
Last Updated

January 15, 2026

Status Verified

January 1, 2026

Enrollment Period

1.9 years

First QC Date

December 25, 2025

Last Update Submit

January 7, 2026

Conditions

Osteoarthritis, Knee

Keywords

Patellar denervationTotal knee arthroplastyTotal knee replacement

Outcome Measures

Primary Outcomes (1)

  • Visual analog scale score for knee pain

    2 weeks, 6 weeks, 3 months, 6 months, and 12 months

Secondary Outcomes (3)

  • Kujala score

    3 months, 1 year

  • Knee Society score

    3 months, 1 year

  • Timed up and go test

    3 months, 1 year

Study Arms (2)

Patellar Denervation

EXPERIMENTAL
Procedure: Patellar Denervation

Non-Patellar Denervation

NO INTERVENTION

Interventions

Patellar DenervationPROCEDURE

Electrocautery patella circumferentially during total knee arthroplasty

Patellar Denervation

Eligibility Criteria

Age55 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 55-85 years old
  • Knee osteoarthritis
  • Plan for total knee arthroplasty after failed conservative treatment for at least 3 months

You may not qualify if:

  • Previous history of trauma, fracture or open surgery on the same knee
  • Inflammatory arthritis or Crystal-induced arthritis
  • Patellar instability or isolated patellofemoral osteoarthritis
  • Unable to answer questionnaire
  • Cannot tolerate surgery due to medical comorbidities

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chalathorn Kulthonchalanan

Chon Buri, Changwat Chon Buri, 20110, Thailand

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 25, 2025

First Posted

January 15, 2026

Study Start

August 8, 2023

Primary Completion

June 21, 2025

Study Completion

June 21, 2025

Last Updated

January 15, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Data was save in form of Google sheet

Locations

TH(1)