A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers

NCT07337109 | Recruiting

• 1 other identifier: 400318
• Study Type: observational
• Target: 375
• Locations: 1 country
• Sites: 1

Brief Summary

The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.

Conditions

Dentin Hypersensitivity

Outcome Measures

Primary Outcomes (1)

• Change From Baseline in Total DHEQ Score Over 12 Months

  Change from baseline in total DHEQ score and each of the domain scores (daily restrictions, coping behaviors, personal identity, social impact, emotional impact) over 12 months. The DHEQ has total 15 questions each will be scored on a scale ranging from 1 (strongly disagree) to 7 (strongly agree), thus total possible score will be ranging from 15 to 105, where higher score indicates worst outcome.

  Baseline and up to 12 Months

Secondary Outcomes (5)

• Description of Treatment Selection Over 12 Months

  Up to 12 Months

• Treatment Discontinuation/Switch Over 12 Months

  Up to 12 Months

• Frequency of Treatment Used Over 12 Months

  Up to 12 Months

• Frequency of DH Over 12 Months

  Up to 12 Months

• Frequency of Brushing at Baseline, Months 6 and 12

  Baseline, Months 6 and 12

Study Arms (1)

New sufferers of self-reported Dentin Hypersensitivity aged 18+ years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants who are new sufferers of DH and have begun treating their DH.

You may qualify if:

• Participant who has provided consent indicating they have been informed of all pertinent aspects of the study.
• All genders who, at the time of screening, are aged more than or equal to (\>=)18 years.
• Anyone who has begun to experience dentin hypersensitivity (self-reported) within the past three months.
• Anyone who has started to use products to treat their tooth sensitivity within the past three months.
• Participant who is able to independently complete all activities online.
• Participants residing in the United States.

You may not qualify if:

• Anyone who has any chronic health conditions that could impact their participation in this study, such as cancer, mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period.
• Participant whose sensitivity could be caused by other factors or clinical pathology than DH, as self-reported on the screening questionnaire, which include:
• Anyone who suffers from tooth cavities, significant gum disease, cracked or fractured teeth, temporomandibular joint disease (TMD), or who has had tooth extractions or fillings within the last three months.
• Anyone who wears braces (including Invisalign-like appliances) for treatment or dentures (full or partial).
• Participant who has undergone treatment for periodontal or gum disease within 6 months of screening or is currently undergoing treatment for periodontal or gum disease.
• Participant who has been informed by a Dental Health Care Professional (DHCP) that they have active periodontitis.
• Participant who has been informed by a DHCP that they have active caries.
• Participant with any chronic and/or severe painful health condition(s) which lead to regular use of pain relief medications (more than 3 days a week).
• Anyone who has participated in another dentin hypersensitivity study within the last three months.
• Currently participating in another research study or will be participating in any other research study at any point during this study's duration.

Sponsors & Collaborators

• HALEON: lead

Study Sites (1)

Citruslabs (Virtual Site)

Las Vegas, Nevada, 89118, United States

RECRUITING

MeSH Terms

Conditions

Dentin Sensitivity

Condition Hierarchy (Ancestors)

Tooth Diseases; Stomatognathic Diseases

Central Study Contacts

Haleon Response Center

CONTACT

+441932959500; ww.clinical-trial-register@haleon.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 12, 2025
• First Posted: January 13, 2026
• Study Start: December 16, 2025
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: April 28, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)