Motor Relearning Program Combined With Neck Stabilization Exercises in Subacute Stroke

NCT07332897 | Enrolling By Invitation

• 1 other identifier: UOL/IREB
• Study Type: interventional
• Target: 96
• Locations: 1 country
• Sites: 2

Brief Summary

Stroke is a neurological event that leads to significant motor and functional impairments due to disruption of cerebral blood flow. The subacute phase, typically ranging from day of attack up to three months post-stroke, is a critical window for neuroplasticity and functional recovery. The proposed study will find out the effects of motor relearning program combined with neck stabilization exercises for health-related quality of life, sensorimotor function and upper extremity functionality.

Conditions

Stroke (Subacute)

Keywords

Motor relearning program, neck stabilization exercises, stroke (subacute)

Outcome Measures

Primary Outcomes (3)

• Sensorimotor Function

  Sensorimotor function will be assessed by using Urdu translated version of Fugl-Meyer Assessment (FMA) for Upper Extremity (UE)

  Four weeks

• Upper Limb Functionality

  Functionality, assessed by using Wolf Motor Functional Test

  Four weeks

• Health Related Quality of Life

  Health Related Quality of life will be assessed by using Stroke Impact Scale

  Four weeks

Study Arms (2)

nterventional Group A

EXPERIMENTAL

Experimental: Interventional Group A These patients will be treated by neck stabilization exercises and motor relearning program with 3 sets of 10 repetitions each and 10 seconds along with 10 successful attempts in one session. Delivered five times a week for four weeks For this, participants will be given a comfortable assisted sitting and transition to standing position.

Other: Motor relearning program combined with neck stabilization exercises

Interventional Group B

ACTIVE COMPARATOR

Active Comparator: Interventional Group B These patients will be treated by routine physical therapy exercises with motor relearning program with three sets of 10 repetitions each, squeeze hold for 10 seconds, stretch hold for 30 seconds repetitions in one session for 4 weeks, five times every week. For this, participants will be given a comfortable supine lying transition to assisted sitting position.

Other: Motor relearning program combined with routine physical therapy

Interventions

Motor relearning program combined with neck stabilization exercises OTHER

Neck stabilization exercises and Motor relearning program based functional activities will be performed

nterventional Group A

Motor relearning program combined with routine physical therapy OTHER

Routine Physical therapy exercises and Motor relearning program based functional activities will be performed

Interventional Group B

Eligibility Criteria

• Age: 35 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients diagnosed for stroke in subacute phase by a neurologist
• Patients with Mini Mental State Examination score of 24 and above

You may not qualify if:

• Patients with accompanying mental Disorders (unable to cooperate)
• Fracture of upper limb in last 6 months
• Recent surgery of upper periphery effecting mobility and motor functionality
• Non consenting to intervention

Sponsors & Collaborators

• University of Lahore: lead

Study Sites (2)

Shadman Medical Center

Lahore, Punjab Province, 54000, Pakistan

Location

The University of Lahore Teaching Hospital

Lahore, Punjab Province, 54000, Pakistan

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 30, 2025
• First Posted: January 12, 2026
• Study Start: December 11, 2025
• Primary Completion: April 20, 2026
• Study Completion: April 20, 2026
• Last Updated: January 12, 2026

Record last verified: 2025-12

Locations

PA (2)