NCT07332026

Brief Summary

The aim of the present study will be directed to evaluate the clinical and radiographic success of adult pulpotomies in type 2 diabetic and non-diabetic patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2023

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

December 13, 2025

Completed
1 month until next milestone

First Posted

Study publicly available on registry

January 12, 2026

Completed
Last Updated

January 12, 2026

Status Verified

December 1, 2025

Enrollment Period

12 months

First QC Date

December 13, 2025

Last Update Submit

December 28, 2025

Conditions

Adult Pulpotomy Success in Diabetic Patients

Outcome Measures

Primary Outcomes (1)

  • Outcome assessment

    Assessment of outcome was done using the technique described by Zanini et al. Each patient was evaluated at different time intervals; Treatment was considered successful if there was an intact final restoration, an asymptomatic tooth, and the periapical index score was 1. Treatment was considered Uncertain if the final restoration is intact, asymptomatic tooth, and the periapical index score of 2. Treatment was considered a failure if there was not an intact final restoration, irrelevant clinical symptoms and an irrelevant periapical index score. Treatment was considered a failure if there was an intact final restoration with symptoms and an irrelevant periapical index score. * Treatment was considered a failure if there was an intact final restoration, irrelevant clinical symptoms, and the periapical index was 3 or more.

    3, 6, 12 months

Study Arms (2)

diabetic

EXPERIMENTAL

type 2 diabetic patients

Procedure: pulpotomy

non-diabetic

EXPERIMENTAL

healthy patients

Procedure: pulpotomy

Interventions

pulpotomyPROCEDURE

complete excision of coronal pulp

diabeticnon-diabetic

Eligibility Criteria

Age30 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
lower first or second molar diagnosed with irreversible pulpitis in diabetic and non-diabetic patients

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Moataz A AlKhawas

Cairo, 11651, Egypt

Location

MeSH Terms

Interventions

Pulpotomy

Intervention Hierarchy (Ancestors)

EndodonticsDentistry

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 13, 2025

First Posted

January 12, 2026

Study Start

January 1, 2023

Primary Completion

December 31, 2023

Study Completion

December 31, 2023

Last Updated

January 12, 2026

Record last verified: 2025-12

Locations

EG(1)