NCT07331571

Brief Summary

The study was conducted to determine the effects of myofascial release therapy with and without autogenic inhibition muscle energy technique in patients with non-specific chronic neck pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 13, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2025

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 29, 2025

Completed
14 days until next milestone

First Posted

Study publicly available on registry

January 12, 2026

Completed
Last Updated

January 12, 2026

Status Verified

December 1, 2025

Enrollment Period

5 months

First QC Date

December 29, 2025

Last Update Submit

December 29, 2025

Conditions

Keywords

Neck AcheMyofascial Release TherapyAutogenic Inhibition TechniqueMuscle Energy TechniqueChronic Neck Pain

Outcome Measures

Primary Outcomes (2)

  • Numeric Pain Rating Scale

    Numeric Pain Rating Scale is utilized to evaluate pain. It consists of 11 points, having an overall score ranging from 0 and 10, where: 0 represents no pain, 1 - 3 represents mild pain, 4 - 6 represents moderate pain and 7 - 10 represents the most severe pain.

    From enrollment to the end of treatment at 6 weeks

  • Neck Disability Index

    Neck Disability Index is a questionnaire that has 10-questions for determining cervical pain and functional disability linked with the activities of daily living. It consists of questions on pain intensity, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation. Scores in each item is described in 6 stages, from 0 to 5 points. The total of 0-4 points indicate no disability, 5-14 points indicate mild disability, 15-24 points indicate moderate disability, 25-34 points indicate severe disability and 35-50 points indicate complete disability

    From enrollment to the end of treatment at 6 weeks

Secondary Outcomes (6)

  • ROM Cervical Spine (Flexion)

    From enrollment to the end of treatment at 6 weeks

  • ROM Cervical Spine (Extension)

    From enrollment to the end of treatment at 6 weeks

  • ROM Cervical Spine (Lateral Flexion) Left Side

    From enrollment to the end of treatment at 6 weeks

  • ROM Cervical Spine (Lateral Flexion) Right Side

    From enrollment to the end of treatment at 6 weeks

  • ROM Cervical Spine (Rotation) Left Side

    From enrollment to the end of treatment at 6 weeks

  • +1 more secondary outcomes

Study Arms (2)

Myofascial Release with Autogenic Inhibition Muscle Energy Technique

EXPERIMENTAL
Other: Autogenic Inhibition Muscle Energy TechniqueOther: Myofasical Release TherapyOther: Standardized Physiotherapy Treatment

Myofascial Release Therapy

ACTIVE COMPARATOR
Other: Myofasical Release TherapyOther: Standardized Physiotherapy Treatment

Interventions

AI MET was applied for upper trapezius 5 times for each side, similarly for levator scapulae it was applied 5 times for each side. AI MET was applied for posterior, middle and anterior fibres of scalene muscle. For sternocleidomastoid muscle it was applied for at least twice for each side. 8 sessions were conducted for 6 weeks, with 3 sessions scheduled every week.

Myofascial Release with Autogenic Inhibition Muscle Energy Technique

MFR for upper trapezius and levator scapulae was carried out 5 times for each side. A total of 18 sessions were conducted for 6 weeks, with 3 sessions scheduled every week.

Myofascial Release TherapyMyofascial Release with Autogenic Inhibition Muscle Energy Technique

Electric hot pack for 10 minutes for 10 minutes, TENS with frequency of 120Hz at low intensity having pulse duration of 50-200μs for 10 minutes \& Grade I and II Maitland posteroanterior central glide with 3 sets of 30 oscillations, for alleviation of pain at the target vertebral segment.

Myofascial Release TherapyMyofascial Release with Autogenic Inhibition Muscle Energy Technique

Eligibility Criteria

Age20 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Neck pain for at least 3 months
  • Pain intensity on NPRS between 4 to 7
  • Limited neck range of motion
  • Use of computer for at least 2 hours daily
  • Negative Sharp-Purser and alar ligaments test (to rule out atlantoaxial instability, integrity of transverse and alar ligaments)

You may not qualify if:

  • History of trauma
  • Cervical spine fracture
  • Open neck surgery
  • Cervical radiculopathy
  • Paresthesia
  • Cervical myelopathy
  • Rheumatoid Arthritis
  • Ankylosing Spondylitis
  • Multiple Sclerosis
  • Fibromyalgia
  • Hemorrhage tendency and/or anticoagulation treatment
  • Whiplash Injury

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rehab Max Physio & Sports Injury Clinic

Layyah, Punjab Province, 31200, Pakistan

Location

MeSH Terms

Conditions

Neck Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Shakil ur Rehman, Ph.D

    Riphah International University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 29, 2025

First Posted

January 12, 2026

Study Start

January 13, 2025

Primary Completion

May 31, 2025

Study Completion

October 31, 2025

Last Updated

January 12, 2026

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations