NCT07330115

Brief Summary

This study is conducted to investigate:

  1. 1.The efficiency of combination of KT and proprioceptive exercises on neck proprioception in patients with CR.
  2. 2.The efficiency of combination of KT and proprioceptive exercises on neck pain, neck function and neuropathic pain in patients with CR.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 17, 2025

Completed
23 days until next milestone

First Posted

Study publicly available on registry

January 9, 2026

Completed
11 days until next milestone

Study Start

First participant enrolled

January 20, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2026

Completed
Last Updated

January 12, 2026

Status Verified

January 1, 2026

Enrollment Period

1 month

First QC Date

December 17, 2025

Last Update Submit

January 9, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Cervical proprioception

    The most common method used for assessment of cervical proprioception is Joint Position Error test, the active movement angle reproduction test, which requires the subject to relocate a neutral head position or a target head position selected by the investigator (Loudon et al., 1997; Hillier et al., 2015). In head position sense measurement studies, the variable measured is the difference between the reference point position entrenched initially (either a neutral or target position) and the position produced by the subject when attempting to match the target position , This difference is called JPE and has angular units of degrees (°) (Hillier et al., 2015). JPE test demonstrates good intra- and inter-rater reliability and acceptable validity for evaluating cervical proprioception (Revel et al., 1991; Kristjansson et al., 2003). JPE test will be measured by Laser Pointer Device.

    Baseline and 4 weeks

Secondary Outcomes (3)

  • Cervical pain

    at baseline and after 4 weeks

  • Function

    at baseline and after 4 weeks.

  • Radicular pain

    at baseline and after 4 weeks.

Study Arms (3)

proprioceptive neck exercises group

ACTIVE COMPARATOR

Proprioceptive neck exercises The patient will sit on a swivel chair with a backrest in front of a wall at a distance of 90 cm. A laser pointer will be fixed to the highest point of the patient's head, so the laser light will be projected on a target hanging on the wall . Then active cervical movements will be performed.

Other: proprioceptive neck exercises

KT group

ACTIVE COMPARATOR

Group B will receive KT.

Other: Kinesiotaping

KT and proprioceptive neck exercises

ACTIVE COMPARATOR

Group C will receive both (proprioceptive neck exercercises and KT)

Other: proprioceptive neck exercisesOther: Kinesiotaping

Interventions

Proprioceptive craniocervical exercises The patient will sit on a swivel chair with a backrest in front of a wall at a distance of 90 cm. A laser pointer will be fixed to the highest point of the patient's head, so the laser light will be projected on a target hanging on the wall (Espí-López et al., 2020). Then active cervical movements will be performed.

KT and proprioceptive neck exercisesproprioceptive neck exercises group

For kinesio tape application, a method of brachial plexus application will be chosen .

KT and proprioceptive neck exercisesKT group

Eligibility Criteria

Age35 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age from 35-50years (Rafiq et al. 2022).
  • BMI from 18 to 29.9 kg /m2 (Morsi et al., 2022.
  • Current continuous or intermittent pain that has persisted for more than 3 months (Persson et al., 1997, Purves et al., 1998).
  • Paresthesia or numbness along the course of the nerve (Young et al., 2009).
  • Positive response for the 4 Wainner RS et al., test's item cluster:
  • Ipsilateral cervical Spurling.
  • Upper Limb Tension Tests (ULTTs).
  • Neck Distraction.
  • Spurling tests range (ROM) less than 60° (Wainner et al., 2003).
  • Unilateral affection in the upper limb.

You may not qualify if:

  • History of surgical procedures for pathologies giving rise to neck pain or CTS (Wainner et al., 2003).
  • Clinical signs or symptoms of medical "red flags" or serious pathology (infection, cancer, and cardiac involvement) (George et al., 2015).
  • Any systematic disease such as rheumatism and tuberculosis, cervical myelopathy, or multiple sclerosis (Joghataei et al., 2004).
  • Systemic disease is known to cause generalized peripheral neuropathy as diabetes millitus (Wainner et al., 2003).
  • Upper Motor neuron disease such as stroke and amyotrophic lateral sclerosis (ALS) (Joghataei et al., 2004).
  • Complete loss of sensation along the involved nerve root (Moustafa \& Diab, 2014).
  • Primary report of bilateral radiating arm pain (Wainner et al., 2003)
  • Pregnant woman (Moustafa \& Diab, 2014).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (4)

  • Ferlinc A, Fabiani E, Velnar T, Gradisnik L. The Importance and Role of Proprioception in the Elderly: a Short Review. Mater Sociomed. 2019 Sep;31(3):219-221. doi: 10.5455/msm.2019.31.219-221.

  • Espi-Lopez GV, Aguilar-Rodriguez M, Zarzoso M, Serra-Ano P, Martinez DE LA Fuente JM, Ingles M, Marques-Sule E. Efficacy of a proprioceptive exercise program in patients with nonspecific neck pain: a randomized controlled trial. Eur J Phys Rehabil Med. 2021 Jun;57(3):397-405. doi: 10.23736/S1973-9087.20.06302-9. Epub 2020 Oct 13.

  • Caridi JM, Pumberger M, Hughes AP. Cervical radiculopathy: a review. HSS J. 2011 Oct;7(3):265-72. doi: 10.1007/s11420-011-9218-z. Epub 2011 Sep 9.

  • Agyenkwa SK, Mustafaoglu R, Yeldan I. Therapeutic Effects of Kinesiology Taping Versus Self-Mobilization on Neck Pain, Proprioception, Muscle Activity, and Respiratory Muscle Strength Among Prolonged Electronic Device Users. A Randomized Controlled Trial. Physiother Res Int. 2025 Apr;30(2):e70061. doi: 10.1002/pri.70061.

MeSH Terms

Conditions

Radiculopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System Diseases

Study Officials

  • Eman A kamel, lecturer

    cairo university in Egypt

    STUDY DIRECTOR

Central Study Contacts

Fadia A Fawzy, Bachelor's

CONTACT

Enas F Youssef, Professor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned into three parallel groups. The first group will receive proprioceptive neck exercises only, the second group will receive kinesio taping only, and the third group will receive a combination of both interventions. All groups will receive their assigned intervention throughout the study period.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

December 17, 2025

First Posted

January 9, 2026

Study Start

January 20, 2026

Primary Completion

March 1, 2026

Study Completion

April 1, 2026

Last Updated

January 12, 2026

Record last verified: 2026-01