Comparison of Scoring Systems in Gastrointestinal Cancer Surgery

NCT07325656 | Completed

• 1 other identifier: LutfiKırdarCityHospital
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Accurate prediction of postoperative morbidity and mortality is essential for optimizing perioperative management in patients undergoing gastrointestinal cancer surgery. This study evaluates the predictive performance of commonly used perioperative risk scoring systems in patients undergoing gastrointestinal surgery for malignancy under general anesthesia.

Conditions

Gastro Intestinal Cancer; Scoring Systems

Keywords

mortality; morbidity

Outcome Measures

Primary Outcomes (1)

• 30- and 60-day All-Cause Postoperative Mortality

  All-cause mortality within 30 and 60 days after gastrointestinal malignancy surgery performed under general anesthesia. Mortality data will be obtained from hospital records and verified through national health databases.

  60 days after surgery

Secondary Outcomes (1)

• Postoperative Pulmonary Complications

  Within 30 days after surgery

Other Outcomes (1)

• Postoperative Non-Pulmonary Complications

  Within 30 days after surgery

Study Arms (1)

Gastrointestinal Cancer Surgery Cohort

Prospective observational group including adult patients undergoing elective surgery for gastrointestinal malignancy. Risk prediction scores will be recorded pre- and peri-operatively.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population includes adult patients (≥18 years) scheduled for elective gastrointestinal malignancy surgery performed under general anesthesia at a tertiary referral hospital. Participants are followed prospectively from the preoperative assessment through the postoperative period. Demographic characteristics, baseline clinical data, and operative variables are collected. Postoperative clinical outcomes are assessed to evaluate the predictive performance of perioperative risk scoring systems for postoperative morbidity and mortality.

Sponsors & Collaborators

• Lütfi Kırdar City Hospital: lead

Study Sites (1)

Kartal Dr. Lutfi Kirdar City Hospital

Istanbul, Kartal, 34899, Turkey (Türkiye)

Location

Related Publications (3)

• Vashistha N, Singhal S, Budhiraja S, Singhal D. Evaluation of ACS-NSQIP and CR-POSSUM risk calculators for the prediction of mortality after colorectal surgery: A retrospective cohort study. J Minim Access Surg. 2024 Apr 1;20(2):142-147. doi: 10.4103/jmas.jmas_187_22. Epub 2022 Sep 12.

  PMID: 36124474 RESULT

• Nag DS, Dembla A, Mahanty PR, Kant S, Chatterjee A, Samaddar DP, Chugh P. Comparative analysis of APACHE-II and P-POSSUM scoring systems in predicting postoperative mortality in patients undergoing emergency laparotomy. World J Clin Cases. 2019 Aug 26;7(16):2227-2237. doi: 10.12998/wjcc.v7.i16.2227.

  PMID: 31531317 RESULT

• Crea N, Di Fabio F, Pata G, Nascimbeni R. APACHE II, POSSUM, and ASA scores and the risk of perioperative complications in patients with colorectal disease. Ann Ital Chir. 2009 May-Jun;80(3):177-81.

  PMID: 20131533 RESULT

Study Officials

• MEHMET E GECICI, MD

  Kartal Dr. Lutfi Kirdar City Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 60 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist Physician

Study Record Dates

• First Submitted: November 30, 2025
• First Posted: January 8, 2026
• Study Start: February 1, 2021
• Primary Completion: August 28, 2021
• Study Completion: August 31, 2021
• Last Updated: January 20, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)