Active Locomotion of Magnetically Controlled Capsule Endoscopy in the Small Bowel: A Feasibility Study

NCT07325344 | Recruiting DMC

• 1 other identifier: KYLL-2025-10-008-1
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to evaluate the responsiveness of the capsule endoscope to the attitude controller and to investigate its active locomotion performance within the small bowel.

Conditions

Capsule Endoscopy

Keywords

capsule endoscopy; small bowel disease; locomotion

Outcome Measures

Primary Outcomes (1)

• capsule endoscope's responsiveness to the attitude controller

  Excellent: The magnetically controlled capsule endoscope can precisely follow the attitude controller to move to the target area. Moderate: The magnetically controlled capsule endoscope can follow the attitude controller's movement, but cannot be accurately guided to the target area. Poor: There are signs of magnetic attraction, but the capsule does not follow the movement of the attitude controller.

  During performing double-balloon enteroscope

Study Arms (1)

subject

EXPERIMENTAL

During the routine air/water insufflation phases of the enteroscopy, the researchers will attempt to guide the capsule's movement using an external magnetic control device.

Device: magnetic control

Interventions

magnetic control DEVICE

Intervention: On the day of the examination, the subject will swallow the capsule endoscope. This will be followed by a standard enteroscopy procedure. During the routine air/water insufflation phases of the enteroscopy, the researchers will attempt to guide the capsule's movement using an external magnetic control device.

subject

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients scheduled to undergo enteroscopy.

You may not qualify if:

• Patients with severe dysfunction of vital organs (e.g., heart, lungs). Patients with small bowel obstruction precluding adequate bowel preparation. Patients with a history of multiple abdominal surgeries. Patients with implanted devices such as cardiac pacemakers or metal implants. Patients with other high-risk conditions or lesions (e.g., moderate-to-severe esophagogastric varices, massive ascites).
• Patients who are pregnant or lactating. Patients unable or unwilling to provide informed consent.

Sponsors & Collaborators

• Shandong University: lead

Study Sites (1)

Qilu Hospital of Shandong University

Jinan, Shandong, 250012, China

RECRUITING

Central Study Contacts

Xiuli Zuo, MD,PhD

CONTACT

+86-18560080066; zuoxiuli@sdu.edu.cn

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director of Gastroenterology Department

Study Record Dates

• First Submitted: December 16, 2025
• First Posted: January 8, 2026
• Study Start: December 1, 2025
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: January 8, 2026

Record last verified: 2026-01

Locations

CN (1)