NCT07321223

Brief Summary

COMPARISON OF DIFFERENT DOSES OF VITAMIN D SUPPLEMENTATION ON GLYCATED HEMOGLOBIN (HbA1c) and BLOOD GLUCOSE PARAMETRS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS HAVING VITAMIN D DEFICIENCY"

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
108

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2024

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 22, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 22, 2024

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

December 21, 2025

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 6, 2026

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 22, 2026

Completed
Last Updated

January 6, 2026

Status Verified

June 1, 2025

Enrollment Period

3 months

First QC Date

December 21, 2025

Last Update Submit

December 21, 2025

Conditions

Diabetes (DM)Vitamin D Deficiency

Keywords

Diabetes MellitusVitamin D Deficiency

Outcome Measures

Primary Outcomes (1)

  • HbA1c

    90 days

Secondary Outcomes (1)

  • Blood Safety Profile (LFTs, RFTs)

    90 days

Study Arms (3)

Treatment Group-1

EXPERIMENTAL

Treatment vitamin D capsules with different dosage (50,000IU) once a week for 90days

Dietary Supplement: Vitamin D

Placebo

NO INTERVENTION

Only Metformin and Balance Diet

Treatment Group 2

EXPERIMENTAL

Treatment vitamin D capsules with different dosage (200000IU) once a week for 90days

Dietary Supplement: Vitamin D

Interventions

Vitamin DDIETARY_SUPPLEMENT

Vitamin D supplement capsules (50,000 IU, 200000 IU)

Treatment Group 2Treatment Group-1

Eligibility Criteria

Age40 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may not qualify if:

  • Inability or unwilling to participate or Clinical proximal myopathy
  • Renal, hepatic, endocrinological disorders or malignancies on basis of history
  • Serum calcium levels \> 10.5mg/dl
  • Use of insulin or any change in dosage of current hypoglycemic medications during last 3 months
  • Intake of vitamin D, calcium or omega 3 supplements within the past 3 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

PAF Hospital

Islamabad, Pakistan

Location

MeSH Terms

Conditions

Diabetes MellitusVitamin D Deficiency

Interventions

Vitamin D

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAvitaminosisDeficiency DiseasesMalnutritionNutrition Disorders

Intervention Hierarchy (Ancestors)

SecosteroidsSteroidsFused-Ring CompoundsPolycyclic Compounds

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 21, 2025

First Posted

January 6, 2026

Study Start

August 22, 2024

Primary Completion

November 22, 2024

Study Completion

February 22, 2026

Last Updated

January 6, 2026

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will share

Locations

PA(1)