Preoperative Vitamin D Levels and Respiratory Complications of General Anesthesia

NCT03342651 | Completed

• 1 other identifier: DVIT1
• Study Type: interventional
• Target: 95
• Locations: 0 countries
• Sites: N/A

Brief Summary

Vitamin D deficiency is a commonly observed health problem in the world. With a role in many chronic diseases and especially lung diseases, the importance of vitamin D deficiency in anesthesia management is increased. This research aims to investigate whether there is a correlation between the respiratory complications occurring in patients under general anesthesia and preoperative vitamin D levels.

Conditions

Vitamin D Deficiency

Keywords

Vitamin D; general anesthesia; respiratory complications

Outcome Measures

Primary Outcomes (1)

• Relationship between Vitamin D levels and respiratory complications

  Low vitamin D levels may be a potential risk in terms of respiratory complications related to general anesthesia

  Perioperative period

Study Arms (1)

Observational research

OTHER

Vitamin D levels and respiratory complications; observational research.

Other: Vitamin D

Interventions

Vitamin D OTHER

Vitamin D, general anesthesia, respiratory complications

Also known as: Anesthesia, respiratory complications

Observational research

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \- American Society of Anesthesiologists I - II risk classification, healthy adult surgery cases

You may not qualify if:

• Thoracic surgery, those with severe respiratory, neuromuscular or endocrine system diseases, those with difficult intubation, morbid obesity, using vitamin D supplements and those who smoked

Sponsors & Collaborators

• Ordu University: lead

Related Publications (10)

• Hutchinson K, Healy M, Crowley V, Louw M, Rochev Y. Verification of Abbott 25-OH-vitamin D assay on the architect system. Pract Lab Med. 2017 Jan 17;7:27-35. doi: 10.1016/j.plabm.2017.01.001. eCollection 2017 Apr.

  PMID: 28856215 RESULT

• Turan A, Hesler BD, You J, Saager L, Grady M, Komatsu R, Kurz A, Sessler DI. The association of serum vitamin D concentration with serious complications after noncardiac surgery. Anesth Analg. 2014 Sep;119(3):603-612. doi: 10.1213/ANE.0000000000000096.

  PMID: 25121616 RESULT

• Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008 Apr;87(4):1080S-6S. doi: 10.1093/ajcn/87.4.1080S.

  PMID: 18400738 RESULT

• Bener A, Ehlayel MS, Bener HZ, Hamid Q. The impact of Vitamin D deficiency on asthma, allergic rhinitis and wheezing in children: An emerging public health problem. J Family Community Med. 2014 Sep;21(3):154-61. doi: 10.4103/2230-8229.142967.

  PMID: 25374465 RESULT

• Columbo M, Panettieri RA Jr, Rohr AS. Asthma in the elderly: a study of the role of vitamin D. Allergy Asthma Clin Immunol. 2014 Sep 5;10(1):48. doi: 10.1186/1710-1492-10-48. eCollection 2014.

  PMID: 25221606 RESULT

• Banerjee A, Panettieri R Jr. Vitamin D modulates airway smooth muscle function in COPD. Curr Opin Pharmacol. 2012 Jun;12(3):266-74. doi: 10.1016/j.coph.2012.01.014. Epub 2012 Feb 25.

  PMID: 22365730 RESULT

• Quraishi SA, Camargo CA Jr. Vitamin D in acute stress and critical illness. Curr Opin Clin Nutr Metab Care. 2012 Nov;15(6):625-34. doi: 10.1097/MCO.0b013e328358fc2b.

  PMID: 23075939 RESULT

• Mulligan JK, Nagel W, O'Connell BP, Wentzel J, Atkinson C, Schlosser RJ. Cigarette smoke exposure is associated with vitamin D3 deficiencies in patients with chronic rhinosinusitis. J Allergy Clin Immunol. 2014 Aug;134(2):342-9. doi: 10.1016/j.jaci.2014.01.039. Epub 2014 Mar 31.

  PMID: 24698317 RESULT

• Ginde AA, Mansbach JM, Camargo CA Jr. Vitamin D, respiratory infections, and asthma. Curr Allergy Asthma Rep. 2009 Jan;9(1):81-7. doi: 10.1007/s11882-009-0012-7.

  PMID: 19063829 RESULT

• Bartley J. Vitamin D, innate immunity and upper respiratory tract infection. J Laryngol Otol. 2010 May;124(5):465-9. doi: 10.1017/S0022215109992684. Epub 2010 Jan 13.

  PMID: 20067648 RESULT

MeSH Terms

Conditions

Vitamin D Deficiency

Interventions

Vitamin D; Anesthesia

Condition Hierarchy (Ancestors)

Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Secosteroids; Steroids; Fused-Ring Compounds; Polycyclic Compounds; Anesthesia and Analgesia

Study Officials

• Nilay Taş, Assoc.Prof.

  Ordu University, Turkey

  PRINCIPAL INVESTIGATOR

• Tevfik Noyan, Prof.

  Ordu University, Turkey

  STUDY CHAIR

• Özgür Yağan, Assoc. Prof.

  Ordu University, Turkey

  STUDY CHAIR

• Volkan Hancı, Prof.

  Ordu University, Turkey

  STUDY CHAIR

• Ebru Çanakçı, Ass. Prof.

  Ordu University, Turkey

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: October 8, 2017
• First Posted: November 17, 2017
• Study Start: April 1, 2015
• Primary Completion: April 1, 2016
• Study Completion: December 31, 2016
• Last Updated: November 17, 2017

Record last verified: 2017-11

Data Sharing

• IPD Sharing: Will not share