NCT07320365

Brief Summary

This study aims to examine the effects of a newly developed training program on the empathy of healthcare students. The objectives are: (i) designing and implementing an User Interface (UI) using Unity featuring 3D virtual clients representing individuals with physical disabilities, bodily discomforts, and psychosocial disturbances, paired with a chatbot interface for interactive questions-and-answers; (ii) developing a brief empathy training program incorporating AI-generated virtual clients into traditional teaching methods, including didactic lectures, skills rehearsal, mindfulness-based training, and practice with AI-generated virtual clients; and (iii) assessing the impact of this training program on the empathetic attitude, empathetic communication skills, and cognitive flexibility of healthcare students.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
108

participants targeted

Target at P50-P75 for not_applicable

Timeline
7mo left

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress32%
Feb 2026Dec 2026

First Submitted

Initial submission to the registry

December 12, 2025

Completed
25 days until next milestone

First Posted

Study publicly available on registry

January 6, 2026

Completed
26 days until next milestone

Study Start

First participant enrolled

February 1, 2026

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

10 months

First QC Date

December 12, 2025

Last Update Submit

April 8, 2026

Conditions

Keywords

EmpathyAI-generated virtual clients

Outcome Measures

Primary Outcomes (1)

  • Interpersonal Reactivity Index

    The Interpersonal Reactivity Index (IRI) will be used to assess self-reported empathetic attitude. IRI consists of 4 subscale with 28 items rating on a 5 - point Likert scale (0 - 4). Score ranges from 0 - 112, higher score means better empathy.

    Baseline assessment (prior to any training), (ii) immediate post-training assessment (immediately after the final training session, end of week 1), and (iii) 1-month follow-up assessment (approximately 4 weeks after the final training session).

Secondary Outcomes (2)

  • Consultation and Relational Empathy

    Baseline assessment (prior to any training), (ii) immediate post-training assessment (immediately after the final training session, end of week 1), and (iii) 1-month follow-up assessment (approximately 4 weeks after the final training session).

  • Cognitive Flexibility Inventory

    Baseline assessment (prior to any training), (ii) immediate post-training assessment (immediately after the final training session, end of week 1), and (iii) 1-month follow-up assessment (approximately 4 weeks after the final training session).

Study Arms (2)

Control

NO INTERVENTION

Intervention

EXPERIMENTAL

Participants in the intervention group will undertake two sessions, each lasting four hours, of empathy training over a one-week period with group size of 6 to 8 participants. The first training session consists of a 4-hour didactic component focused on empathy frameworks and communication strategies. The second training session includes a 2-hour mindfulness training component followed by a 2-hour AI demonstration and practice component where participants engage with virtual client scenarios.

Other: Empathy training

Interventions

Participants in the intervention group will undertake two sessions, each lasting four hours, of empathy training over a one-week period with group size of 6 to 8 participants. The empathy training will base on our newly developed protocol, including: (i) didactic lectures; (ii) practical skills demonstration and role-play, (iii) a mindfulness-based training; and (iv) practice of empathic skills in two different randomly selected scenarios with feedback from the AI system. Each participants will encounter different scenarios that simulate diverse clinical challenges.

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • undergraduate students enrolled in a healthcare-related program
  • no previous experience with empathy-related training
  • no previous experience working in healthcare settings
  • age 18 years or above
  • native Chinese speakers.

You may not qualify if:

  • \- are or were the main carers of people who are disabled or chronically ill because empathy may be promoted through experience.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hong Kong Metropolitan University

Ho Man Tin, Kowloon, Hong Kong

RECRUITING

Study Officials

  • Tai Wa Liu, PhD

    Hong Kong Metropolitan University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

December 12, 2025

First Posted

January 6, 2026

Study Start

February 1, 2026

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

April 13, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

Non-identifiable individual participant data is available upon reasonable request to the corresponding author after the report published.

Locations