NCT07320118

Brief Summary

Observational study to assess the effectiveness of cell therapy for the treatment of osteoarthritis

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
650

participants targeted

Target at P75+ for all trials

Timeline
44mo left

Started Apr 2010

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress81%
Apr 2010Jan 2030

Study Start

First participant enrolled

April 13, 2010

Completed
15.7 years until next milestone

First Submitted

Initial submission to the registry

December 21, 2025

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 6, 2026

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 12, 2030

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 12, 2030

Last Updated

January 8, 2026

Status Verified

December 1, 2025

Enrollment Period

19.8 years

First QC Date

December 21, 2025

Last Update Submit

January 6, 2026

Conditions

Osteoarthritis (OA)

Outcome Measures

Primary Outcomes (1)

  • Cell Therapy Questionnaire

    Cell Therapy Questionnaire CTQ

    At least fifteen months post operation

Study Arms (2)

ACI patiients

Patient must have had ACI surgery at least 10 months prior

Non ACI Patients

Control group of patients who did not have ACI

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients based in the United Kingdom treated at RJAH orthopaedic hospital

You may qualify if:

  • ACI patients or patients receiving an alternative treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

The Robert Jones and Agnes Hunt Orthopaedic Hospital

Oswestry, Sy10 7AG, United Kingdom

RECRUITING

Robert Jones and Agnes Hunt Orthopaedic hospital

Oswestry, United Kingdom

RECRUITING

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 21, 2025

First Posted

January 6, 2026

Study Start

April 13, 2010

Primary Completion (Estimated)

January 12, 2030

Study Completion (Estimated)

January 12, 2030

Last Updated

January 8, 2026

Record last verified: 2025-12

Locations

GB(2)