The CPH-MBD Cohort Dietary Substudy - Comparison of Methods for Dietary Registrations

NCT07312981 | Recruiting DMC

• 1 other identifier: H-25039131
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 2

Brief Summary

The aim of the study is to assess the association between the calcium and phosphorus balance and the stage of kidney disease measured by creatinine clearence in patients with chronic kidney disease stage 4 and 5. The balance is measured a measurement between the recorded diatery intake and the urinary excretion. Additionally a comparison between image based diatery accessment and weighted records will be measured

Conditions

CKD; CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder; Pre-dialysis; Renal Insufficiency Chronic

Keywords

Diet; Humans; Observational; Cohort; Phosphate/urine; Calcium/urine; Mineral bone disorder; Elderly; Calcium Balance; Phosphate Balance

Outcome Measures

Primary Outcomes (2)

• Comparison of diatery photograph method with weighted records.

  The intake of calcium and phosphate assesed by the 24 hour photos and the 72 hour weighing of food and fluid items will be compared.

  3 days

• Calcium and phosphate balance in relation to the stage of kidney disease

  Measured by the diatery intake of calcium and phosphate in relation to the urinary calcium and phosphate excretion

  3 days

Secondary Outcomes (20)

• Urinary Calcium

  3 days

• Urinary phosphate

  3 days

• Calcium intake total and the distribution of vegetarian and animal sources

  3 days

• Phosphate intake total and the distribution of vegetarian and animal sources

  3 days

• sodium intake total and the distribution of vegetarian and animal sources

  3 days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with chronic kidney disease stage 4-5

You may qualify if:

• A glomerular filtration rate of \<30 ml ml/min/1.73m2
• years and above

You may not qualify if:

• None

Sponsors & Collaborators

• University of Copenhagen: lead
• Herlev Hospital: collaborator

Study Sites (2)

Copenhagen University Hospital - Herlev

Herlev, Capital Region, 2730, Denmark

ACTIVE NOT RECRUITING

Herlev Hospital, Dept Nephrology

Herlev, 2730, Denmark

RECRUITING

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Chronic Kidney Disease-Mineral and Bone Disorder

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Rickets; Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases; Calcium Metabolism Disorders; Vitamin D Deficiency; Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Hyperparathyroidism, Secondary; Hyperparathyroidism; Parathyroid Diseases; Endocrine System Diseases

Study Officials

• Jens Rikardt Andersen, MD, MPA, Assoc Prof

  University of Copenhagen

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jens Rikardt Andersen, MD, MPA

CONTACT

004523346654; jra@nexs.ku.dk

Julian Askøe Bluming, RD

CONTACT

004591568528; lft190@alumni.ku.dk

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 17, 2025
• First Posted: December 31, 2025
• Study Start: December 15, 2025
• Primary Completion (Estimated): May 15, 2026
• Study Completion (Estimated): May 15, 2029
• Last Updated: December 31, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

DK (2)