NCT07312019

Brief Summary

Drug-related iatrogenesis is a major public health issue, accounting for a significant proportion of adverse events and hospitalizations in emergency departments. Optimizing prescription management in this context is critical to improve both patient safety and physician efficiency This study aims to evaluate the impact of the POSOS AI-driven device on the medical time required for prescription management in polymedicated patients admitted to emergency departments. The main objective is to establish whether the use of POSOS can reduce transcription time compared to standard electronic management.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
770

participants targeted

Target at P75+ for not_applicable

Timeline
8mo left

Started Jan 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress35%
Jan 2026Jan 2027

First Submitted

Initial submission to the registry

November 17, 2025

Completed
1 month until next milestone

First Posted

Study publicly available on registry

December 31, 2025

Completed
1 day until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2027

Last Updated

January 8, 2026

Status Verified

January 1, 2026

Enrollment Period

1 year

First QC Date

November 17, 2025

Last Update Submit

January 6, 2026

Conditions

Drug-related IatrogenesisEmergency DepartmentArtificial IntelligenceClinical Decision SupportPrescriptionTranscriptionMedicationReconciliation

Keywords

Drug-related iatrogenesisemergency departmentartificial intelligenceclinical decision supportrandomized trialmedicationreconciliationprescriptiontranscription

Outcome Measures

Primary Outcomes (1)

  • Medical time required for the transcription of prescriptions

    Medical time required for the transcription of prescriptions for at-risk polymedicated patients at emergency admission. This is measured by the duration needed to transcribe prescriptions into the structured electronic health record by physicians, assessed by direct observation with a stopwatch

    Day 1

Secondary Outcomes (9)

  • Number of drug-related problems (DRPs) identified per patient

    day 1

  • Proportion and type of transcription errors (medication name or dosage)

    day 1

  • Identification of DRPs by subtype and severity

    day 1

  • Rate of reconciled medication histories and structured documentation

    day 1

  • Time delays between triage, anamnesis, and diagnosis

    day 1

  • +4 more secondary outcomes

Study Arms (2)

Standard prescription

ACTIVE COMPARATOR

Standard prescription management

Other: current hospital-standard databases

PoSOS

EXPERIMENTAL

POSOS-assisted prescription management

Device: Posos

Interventions

PososDEVICE

Prescription management supported by POSOS device (OCR+AI) for structured data entry and clinical decision support

PoSOS
current hospital-standard databasesOTHER

Prescription management using current hospital-standard databases and tools

Standard prescription

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥18 years
  • Admission to emergency department at a participating center
  • Polymedicated patients with prescriptions including ≥8 medication lines (including those for long-term illnesses)
  • Signed informed consent

You may not qualify if:

  • Patient under legal protection/judicial measures (guardianship/custody)
  • Lack of signed informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Amiens

Amiens, 80480, France

Location

MeSH Terms

Conditions

Emergencies

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Aurélien Mary, Pr

CONTACT

33+322088051mary.aurélien@chu-amiens.fr

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 17, 2025

First Posted

December 31, 2025

Study Start

January 1, 2026

Primary Completion (Estimated)

January 1, 2027

Study Completion (Estimated)

January 1, 2027

Last Updated

January 8, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)