NCT07306689

Brief Summary

The objective of the study is to prospectively assess the prevalence of post-traumatic stress disorder (PTSD) symptoms in a population of women who have experienced a diagnosis of ectopic pregnancy. The investigation into the prevalence of PTSD symptoms will aid in better identifying women who may benefit from early psychological intervention.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
20mo left

Started Dec 2025

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress19%
Dec 2025Dec 2027

First Submitted

Initial submission to the registry

December 14, 2025

Completed
1 day until next milestone

Study Start

First participant enrolled

December 15, 2025

Completed
14 days until next milestone

First Posted

Study publicly available on registry

December 29, 2025

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Last Updated

December 29, 2025

Status Verified

December 1, 2025

Enrollment Period

2 years

First QC Date

December 14, 2025

Last Update Submit

December 14, 2025

Conditions

Keywords

ectopic pregnancyPTSD

Outcome Measures

Primary Outcomes (3)

  • Impact of Event Scale - Revised (IES-R) score

    The score obtained from the Impact of Event Scale - Revised (IES-R) questionnaire has a scoring range of 0 to 88 points, with symptom classification according to the following scheme: * 0-23 points: No or mild symptoms * 24-32 points: A significant number of symptoms * 33 points or more: Most symptoms characteristic of PTSD.

    up to 3 months

  • Posttraumatic Stress Disorder Checklist - Specific (PCL-S) score

    The score obtained from Posttraumatic Stress Disorder Checklist - Specific (PCL-S) questionnaire has a scoring range of 17-85 points, with symptom classification according to the following scheme: * 17-29 points: No or few PTSD symptoms * 30-44 points: Moderate to moderately high PTSD symptoms * 45-85 points: Numerous PTSD symptoms.

    up to 3 months

  • Trauma Recovery Measure (TRM) score

    The stage of recovery is presented based on the distance of the score from the mean. There are three possible stages of recovery: * Early Stage of Recovery: Less than 1 standard deviation below the mean (total score of 31 or fewer). * Middle Stage of Recovery: Total score ranging from 32 to 61. * Late Stage of Recovery: More than 1 standard deviation above the mean (total score of 62 or more).

    up to 3 months

Study Arms (1)

Women diagnosed with ectopic pregnancy

The prospective survey study will include women receiving treatment in the Department of Endocrinology and Gynecology, as well as the Department of Gynecology and Gynecological Oncology at the University Hospital in Kraków, due to an ectopic pregnancy diagnosed by the 14th week of gestation. The study plans to enroll 200 women aged 18 to 45 years.

Diagnostic Test: Impact of Event Scale - Revised (IES-R) questionnaireDiagnostic Test: Posttraumatic Stress Disorder Checklist - Specific (PCL-S) questionnaireDiagnostic Test: Trauma Recovery Measure (TRM) questionnaire

Interventions

The test consists of 22 questions that relate to the respondent's feelings, behaviors, and thoughts concerning the traumatic event over the past seven days. For each question, respondents will indicate one of five responses that best reflects their experience: 0 - Not at all 1. \- A little 2. \- Moderately 3. \- Often 4. \- Very often Upon completion of all questions and totaling the points, the scale for symptoms is classified as follows: 0-23 points: No or mild symptoms 24-32 points: A significant number of symptoms 33 points or more: Most symptoms characteristic of PTSD.

Women diagnosed with ectopic pregnancy

This test includes 17 questions related to the behaviors and feelings of the respondent over the past month. Each question is answered using a 5-point scale with assigned points: Not at all - 1 point Sometimes - 2 points Moderately often - 3 points Often - 4 points Very often - 5 points After totaling the points, they are classified as follows: 17-29 points: No or few PTSD symptoms 30-44 points: Moderate to moderately high PTSD symptoms 45-85 points: Numerous PTSD symptoms.

Women diagnosed with ectopic pregnancy

15-item tool designed to assess trauma and the recovery process. The stage of recovery is presented based on the distance of the score from the mean. There are three possible stages of recovery: * Early Stage of Recovery: Less than 1 standard deviation below the mean (total score of 31 or fewer). * Middle Stage of Recovery: Total score ranging from 32 to 61. * Late Stage of Recovery: More than 1 standard deviation above the mean (total score of 62 or more).

Women diagnosed with ectopic pregnancy

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

The prospective survey study will include women receiving treatment in the Department of Endocrinology and Gynecology, as well as the Department of Gynecology and Gynecological Oncology at the University Hospital in Kraków, due to an ectopic pregnancy diagnosed by the 14th week of gestation. The study plans to enroll 200 women aged 18 to 45 years.

You may qualify if:

  • ectopic pregnancy
  • gestational age up to 14 weeks.

You may not qualify if:

  • heterotopic pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Jagiellonian University Medical College, Department of Gynecology and Obstetrics

Krakow, 31-501, Poland

RECRUITING

Jagiellonian University Medical College

Krakow, Poland

RECRUITING

MeSH Terms

Conditions

Pregnancy, EctopicStress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Pregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesStress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Officials

  • Iwona Gawron, PhD, MD

    Jagiellonian University

    STUDY DIRECTOR

Central Study Contacts

Iwona Gawron, PhD, MD

CONTACT

Robert Jach, Prof., PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD, MD

Study Record Dates

First Submitted

December 14, 2025

First Posted

December 29, 2025

Study Start

December 15, 2025

Primary Completion (Estimated)

December 31, 2027

Study Completion (Estimated)

December 31, 2027

Last Updated

December 29, 2025

Record last verified: 2025-12

Locations