Treatment of Ectopic Pregnancy by Low Dose of Methotrexate
Effectiveness and Safety of a New Methotrexate Regimen in Treatment of Undisturbed Tubal Ectopic Pregnancy : A Pilot Prospective Study
1 other identifier
observational
20
0 countries
N/A
Brief Summary
Evaluate the efficacy and safety of the use of low dose regimen of methotrexate in treatment of tubal undisturbed tubal ectopic pregnancy
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Mar 2024
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 24, 2024
CompletedStudy Start
First participant enrolled
March 1, 2024
CompletedFirst Posted
Study publicly available on registry
March 8, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2025
CompletedMarch 8, 2024
February 1, 2024
1 year
January 24, 2024
March 2, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
descriptive measurements of the results of using low dose methotrexate regimen in treatment of tubal undisturbed ectopic pregnancy
we will follow up cases by investigationssand ultrasound and describe the results of using the low dose methotrexate in treatment of tubal undisturbed ectopic pregnancy
7 day
Interventions
use low dose of Methotrexate in treatment of un distectopic tubal pregnancy
Eligibility Criteria
the study will include women with undisturbed ectopic tubal pregnancy Bhcg \< 5000 Haemodynamicaly stable Normal liver and kidney functions Commitment for fullow up untill ectopic pregnancy resolved
You may qualify if:
- undisturbed ectopic tubal pregnancy Bhcg \< 5000
- Haemodynamicaly stable
- Normal liver and kidney functions
- Commitment for fullow up untill ectopic pregnancy resolvede
You may not qualify if:
- disturbed ectopic pregnancy
- Bhcg \>5000
- Persistent abdominal pain
- Lactating women
- women with abnormal liver and kidney functions
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (3)
Marion LL, Meeks GR. Ectopic pregnancy: History, incidence, epidemiology, and risk factors. Clin Obstet Gynecol. 2012 Jun;55(2):376-86. doi: 10.1097/GRF.0b013e3182516d7b.
PMID: 22510618BACKGROUNDPractice Committee of American Society for Reproductive Medicine. Medical treatment of ectopic pregnancy. Fertil Steril. 2008 Nov;90(5 Suppl):S206-12. doi: 10.1016/j.fertnstert.2008.08.049.
PMID: 19007632BACKGROUNDKarol D, Williamson M, Pereira N. Successful Expectant Management of a Tubal Ectopic Pregnancy. J Minim Invasive Gynecol. 2024 Feb;31(2):92-94. doi: 10.1016/j.jmig.2023.11.011. Epub 2023 Nov 30. No abstract available.
PMID: 38042476BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- principal invistigator
Study Record Dates
First Submitted
January 24, 2024
First Posted
March 8, 2024
Study Start
March 1, 2024
Primary Completion
March 1, 2025
Study Completion
March 1, 2025
Last Updated
March 8, 2024
Record last verified: 2024-02
Data Sharing
- IPD Sharing
- Will not share