Prevelance and Severity of Gerd in Patients With Metabolic Syndrome and How Both Affect Together ( Relationship)

NCT07302022 | Not Yet Recruiting

• 1 other identifier: NCT 01234
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this research is to assess the relationship between metabolic syndrome and gastroesophageal reflux disease (GERD). seeking to determine how components of metabolic syndrome contribute to the risk and severity of GERD.

Conditions

Metabolic Syndrome

Outcome Measures

Primary Outcomes (1)

• the prevalence and severity of GERD among patients with metabolic syndrome, as determined by endoscopic assesment

  .endoscopic findings los angles criteria Grade A : one or more mucosal breaks not more than 5mm Grade b: one or more mucosal breaks more than 5mm Grade c : one or more mucosal breaks extending between tops of two mucosal folds but involving less than 75% of esophageal circumference Grade D : one or more mucosal breaks involving 75% of oesophageal circumference

  1 year

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Community sample

You may qualify if:

• \- 2.3.1-Type of the study: This study will be designed as an observational, cross-sectional, analytical study.
• StudySetting: This study will be performed at internal medicine, Assuit University Hospitals
• Studysubjects:
• Adult patients aged 18 years and above.
• Patients diagnosed with metabolic syndrome based on standard criteria (e.g., NCEP ATP III).
• Patients who will undergo upper gastrointestinal (GI) evaluation for GERD symptoms.

You may not qualify if:

• Patients with a history of upper GI surgery.
• Pregnant or lactating women.
• Patients with known malignancy or severe comorbid illness.
• Patients currently taking proton pump inhibitors (PPIs) or other acid-suppressive therapy.
• Unwilling or unable to provide informed consent.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut university hospitals

Asyut, Asyut Governorate, Egypt

Location

MeSH Terms

Conditions

Metabolic Syndrome

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Central Study Contacts

MOSTAFA Hatem Zedan, Resident

CONTACT

+201112844855; mostafahatemzedan12345@gmail.com

Lecturer of internal medicine at Assiut university hospital

CONTACT

01064455652; drmohhakim@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: September 26, 2025
• First Posted: December 24, 2025
• Study Start: December 30, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2027
• Last Updated: December 24, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)