Evaluation of Local Anesthetic Diffusion to the Sciatic Nerve During Adductor Canal Block

NCT07301476 | Recruiting

• 2 other identifiers: APHP2507302025-A00945-44
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

Adductor canal block is an effective analgesic technique for major knee surgery. However, the saphenous nerve block is not sufficient to explain this block's efficiency. It has been shown that adductor canal block can spread to the tibial and fibular nerves through the adductor hiatus. However, this diffusion's frequency has never been measured. The main objective of this study is to assess clinically the frequency of the spread of the adductor canal block to the fibular and tibial nerves.

Conditions

Adductor Canal Syndrome; Sciatic Nerve

Keywords

Adductor Canal; Sciatic Nerve; Local anesthesia diffusion

Outcome Measures

Primary Outcomes (1)

• Frequency of local anesthetic's spread to tibial and fibular nerve

  The primary outcome is the frequency of local anesthetic's spread to tibial and fibular nerve during an adductor canal block, assessed by sensory and motor testing of these nerve territories. Sensorimotor testing will be performed at four hours with loco-regional anaesthesia.

  at 4 hours

Secondary Outcomes (4)

• Frequency of reduction of sensitivity to cold or touch or reduction in MRC score

  at 1 hour and at 4 hours

• Spread of the local anesthetic in the popliteal fossa

  at baseline

• Evaluation of the positive and negative predictive value

  at baseline and 1 hour, 4 hours

• Clinical alteration assessement

  at Baseline and at 1 hour and 4 hours

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will be all the consecutive patients scheduled for elective knee surgery under general anesthesia in our center and receiving an adductor canal block.

You may qualify if:

• patients over 18 years old scheduled for elective knee surgery under general anesthesia
• in our center
• receiving an adductor canal block

You may not qualify if:

• patients cognitively impaired,
• patients suffering from peripheral neuropathy at the lower limb,
• patients receiving an IPACK block or surgical knee infiltration to complete the adductor canal block analgesia.
• patients who refused to take part in this study
• pregnant or breastfeeding patients
• patients under guardianship
• imprisoned patients,
• patients without any medical insurance

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Study Sites (1)

Department of Anesthésia, CHU Raymond Poincaré - APHP

Boulogne-Billancourt, 92100, France

RECRUITING

Study Officials

• Romuald Henry, MD

  CHU Raymond Poincaré - APHP

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Romuald Henry, MD

CONTACT

+ 33 06 72 83 17 51; romuald.henry@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 18, 2025
• First Posted: December 24, 2025
• Study Start: December 10, 2025
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: December 24, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)