Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics

NCT07300878 | Active Not Recruiting Phase 4 DMC FDA Device

• 1 other identifier: F.5.2/2024(ERRC)/PIMS
• Study Type: interventional
• Target: 208
• Locations: 1 country
• Sites: 1

Brief Summary

In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia. For placing this tube laryngoscopy is done which results in increase in blood pressure and heart rate. This study will compare the rise in blood pressure and heart rate among when using video laryngoscope with conventional laryngoscope.

Conditions

Laryngoscopic Stress Response; Video Laryngoscopy; Conventional Laryngoscopy

Keywords

Laryngoscopic stress response; Video laryngoscopy; Conventional laryngoscopy

Outcome Measures

Primary Outcomes (1)

• Heart Rate

  Upon arrival in OR (baseline) then immediately following intubation (T1) and then at 3,5,10 minutes following intubation

Secondary Outcomes (3)

• Mean Blood Pressure

  This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation

• Systolic Blood Pressure

  This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation

• Diastolic Blood Pressure

  This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation

Study Arms (2)

Video laryngoscopy

EXPERIMENTAL

Patient in this group will be intubated using hyperangulated C MAC video laryngoscope

Device: C MAC hyperangulated video laryngoscopy

Conventional Laryngoscopy

ACTIVE COMPARATOR

Patient in this group will be intubated using conventional macintosh laryngoscopic blade

Device: Conventional macintosh laryngoscopy

Interventions

Conventional macintosh laryngoscopy DEVICE

Patient in this group will be intubated using conventional macintosh laryngoscopy

Conventional Laryngoscopy

C MAC hyperangulated video laryngoscopy DEVICE

Patient will be intubated using hyperangulated C MAC video laryngoscope

Video laryngoscopy

Eligibility Criteria

• Age: 16 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Elective surgeries under General Endotracheal Anesthesia. ASA class I and II.

You may not qualify if:

• Pregnancy
• Body mass index \>35 kg/m2
• No teeth
• Maxillofacial trauma
• Limited Cervical spine movement
• Upper Airway Tumors
• Preoperative assessment indicating difficult airway requiring use of video laryngoscope or fiberoptic intubation.

Sponsors & Collaborators

• Pakistan Institute of Medical Sciences: lead

Study Sites (1)

Deparment of Anesthesia PIMS

Islamabad, 44000, Pakistan

Location

Related Publications (1)

• Wang L, Li H, Zhong Y, Ye S, Deng J, Pan T, Zhang Y. Comparative Analysis of Hemodynamic Responses and Oropharyngeal Complications in Tracheal Intubation: Evaluating Conventional, Video, and Rigid Video Laryngoscopes Under General Anesthesia. Med Sci Monit. 2024 Sep 5;30:e944916. doi: 10.12659/MSM.944916.

  PMID: 39233395 BACKGROUND

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 21, 2025
• First Posted: December 24, 2025
• Study Start: December 22, 2025
• Primary Completion (Estimated): June 22, 2026
• Study Completion (Estimated): June 22, 2026
• Last Updated: December 24, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)