Using Implementation Science to Adapt a Targeted Transportation Intervention for Patients With Diabetic Retinopathy (PRONTO-EYE)

NCT07296952 | Recruiting DMC

• 2 other identifiers: 2023-0960K23EY034602
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This is a a type 3 hybrid effectiveness-implementation pilot study to evaluate the PRONTO-EYE intervention, a rideshare transportation program, in patients with diabetic retinopathy with Medicaid insurance on adherence to ophthalmology visits.

Conditions

Diabetic Retinopathy (DR)

Keywords

diabetic retinopathy (DR); transportation; Medicaid

Outcome Measures

Primary Outcomes (1)

• Number of patients that adhere to their scheduled ophthalmology visits

  Proportion of patients who attend their scheduled ophthalmology visit compared to pre-implementation historical controls.

  Baseline up to 6 months

Secondary Outcomes (6)

• Adoption of PRONTO-EYE

  Assessed continuously throughout the up to 6-month feasibility trial, with a final summary at trial completion.

• Appropriateness of PRONTO-EYE

  Implementation outcomes will be assessed throughout the duration of the study

• Feasibility of PRONTO-EYE

  Assessed upon completion of the up to 6-month feasibility trial

• Fidelity of PRONTO-EYE

  Assessed continuously throughout the up to 6-month feasibility trial, with a final summary at trial completion.

• Penetration of PRONTO-EyE

  Assessed continuously throughout the up to 6-month feasibility trial, with a final summary at trial completion.

Study Arms (1)

PRONTO-EYE rideshare intervention offered

EXPERIMENTAL

All eligible patients are invited to participate in PRONTO-EYE, a rideshare transportation program designed to improve adherence to eye care visits among Medicaid patients with diabetic retinopathy. All eligible patients are included in this arm regardless of if they decide to use PRONTO-EYE or not.

Behavioral: PRONTO-EYE

Interventions

PRONTO-EYE BEHAVIORAL

The PROgram for Non-emergency TranspOrtation (PRONTO) - EYE intervention is a rideshare transportation program designed for patients to get to and from their visits. The intervention includes the rideshare as well as a service blueprint of the offering and how all individuals in the health system interact with it.

PRONTO-EYE rideshare intervention offered

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Established patient
• Medicaid insurance
• History of diabetic retinopathy
• Lives within 25 miles of the clinic
• English speaking

Sponsors & Collaborators

• University of Illinois at Chicago: lead
• National Eye Institute (NEI): collaborator

Study Sites (1)

UI Health

Chicago, Illinois, 60647, United States

RECRUITING

MeSH Terms

Conditions

Diabetic Retinopathy

Condition Hierarchy (Ancestors)

Retinal Diseases; Eye Diseases; Diabetic Angiopathies; Vascular Diseases; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Endocrine System Diseases

Central Study Contacts

Angelica Scanzera, OD, MPH

CONTACT

312-996-3937; ascanz@uic.edu

Bhavana Kolli, DHA

CONTACT

312-996-7182

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Ophthalmology and Visual Sciences

Model Details: Hybrid Type 3 effectiveness-implemementation pilot feasibility trial

Study Record Dates

• First Submitted: December 17, 2025
• First Posted: December 22, 2025
• Study Start: February 3, 2026
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 1, 2027
• Last Updated: February 27, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)