Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease

NCT07292311 | Active Not Recruiting

• 1 other identifier: 071125
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Additionally, the study will assess the feasibility and potential benefits of an online therapeutic exercise program supervised by physiotherapists.

Conditions

Chronic Kidney Disease; Renal Insufficiency, Chronic; Muscle Weakness; Sarcopenia; Physical Fitness; Physical Therapy Modalities

Keywords

chronic kidney disease; renal patients; muscle strength assessment; isokinetic testing; surface electromyography; physiotherapy; occupational therapy; functional evaluation; therapeutic exercise

Outcome Measures

Primary Outcomes (3)

• Test-retest reliability of surface EMG (Electromiography) activation.

  RMS (root mean square). microvolts

  7-10 days

• Test-retest reliability of isokinetic strength

  Intraclass Correlation Coefficient - ICC. Strength (kilograms)

  7-10 days

• Change in handgrip and limb strength measured by VALD dynamometry

  strength (kilograms)

  Baseline and 12 weeks

Study Arms (2)

Reliability Assessment

ACTIVE COMPARATOR

Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb

Device: Reliability Assessment

Online Therapeutic Exercise

EXPERIMENTAL

8-10 week supervised online program including resistance and mobility exercises

Behavioral: Online Therapeutic Exercise

Interventions

Reliability Assessment DEVICE

Device: Isokinetic dynamometer and mDurance® surface EMG Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb

Reliability Assessment

Online Therapeutic Exercise BEHAVIORAL

Behavioral: Online therapeutic exercise program 8-10 week supervised online program including resistance and mobility exercises

Online Therapeutic Exercise

Eligibility Criteria

• Age: 18 Years+
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ≥18 years old.
• Diagnosis of chronic kidney disease (hemodialysis, peritoneal dialysis, or kidney transplant).
• Member of ALCER Association (Badajoz or Cáceres).
• Medical clearance for physical testing/exercise.

You may not qualify if:

• Severe cognitive or communication impairment.
• Unstable cardiovascular or musculoskeletal conditions.
• Refusal to provide informed consent.

Sponsors & Collaborators

• University of Extremadura: lead

Study Sites (1)

Facultad de Enfermería y Terapia Ocupacional

Cáceres, Cáceres, 10003, Spain

Location

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Muscle Weakness; Sarcopenia

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Muscular Atrophy; Atrophy; Pathological Conditions, Anatomical

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Investigator

Study Record Dates

• First Submitted: December 5, 2025
• First Posted: December 18, 2025
• Study Start: November 7, 2025
• Primary Completion: January 30, 2026
• Study Completion (Estimated): May 15, 2026
• Last Updated: December 18, 2025

Record last verified: 2025-11

Locations

ES (1)