Optimizing Strategies to Maximize Patient Recruitment Yield
OSPREY
2 other identifiers
interventional
100,000
1 country
1
Brief Summary
This platform trial aims to evaluate the effectiveness of different messaging strategies within a MyChart messaging program for research recruitment. MyChart is a patient portal system within the Electronic Medical Record (EMR), and messages can be sent directly to patients about research opportunities.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2026
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 15, 2025
CompletedFirst Posted
Study publicly available on registry
December 18, 2025
CompletedStudy Start
First participant enrolled
February 19, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
April 1, 2027
February 25, 2026
February 1, 2026
1.1 years
December 15, 2025
February 23, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Rate of "interested" response to recruitment messages
The primary endpoint is the rate at which individuals respond that they are interested in participating in the study to which they are invited. The primary outcome is a binary variable of "interested" response.
Month 12
Secondary Outcomes (6)
Rate of non-response
Month 12
Rate of "not interested" responses
Month 12
Rate of change in MyChart permissions to contact
Month 12
Rate of enrollment among "interested" patients
Month 12
Patient impressions on recruitment messages
Month 12
- +1 more secondary outcomes
Study Arms (4)
Baseline (control) message
ACTIVE COMPARATORPatients in the Emory Healthcare system, who have not opted out of research contact, receiving MyChart messaging for research recruitment using the current standard template.
Positively-valenced message
EXPERIMENTALPatients in the Emory Healthcare system, who have not opted out of research contact, receiving MyChart messaging for research recruitment using a template with inclusion of positively-valenced language describing the study's value.
Payment-inclusive message
EXPERIMENTALPatients in the Emory Healthcare system, who have not opted out of research contact, receiving MyChart messaging for research recruitment using a template containing information about payment to participants.
Positively-valenced, payment-inclusive message
EXPERIMENTALPatients in the Emory Healthcare system, who have not opted out of research contact, receiving MyChart messaging for research recruitment using a template with both positively-valenced language and payment information.
Interventions
The MyChart study recruitment program will send a message based on the current template, which is a brief message with a neutral tone.
The MyChart study recruitment program will send a message based on a template that contains positively-valenced language related to the value/importance of the study.
The MyChart study recruitment program will send a message based on a template that includes more detailed information about participant payment.
The MyChart study recruitment program will send a message based on a template that includes both positively-valenced language and detailed information about participant payment.
Eligibility Criteria
You may qualify if:
- All studies using the MyChart recruitment service are eligible, including both clinical trials and observational studies.
- Not using MyChart for recruitment.
- At least 500 messages sent, 125 for each arm
- All patients receiving messages via MyChart will be included
- Potential eligibility for a study using MyChart requirement based on the planned query/criteria for that study.
You may not qualify if:
- Minor
- Excluded from primary study that is recruiting participants.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Emory Healthcare System
Atlanta, Georgia, 30322, United States
MeSH Terms
Interventions
Study Officials
- PRINCIPAL INVESTIGATOR
Neal Dickert, MD, PhD
Emory University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
December 15, 2025
First Posted
December 18, 2025
Study Start
February 19, 2026
Primary Completion (Estimated)
April 1, 2027
Study Completion (Estimated)
April 1, 2027
Last Updated
February 25, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP
- Time Frame
- Data will be uploaded into a repository at the time of publication of findings from this study.
- Access Criteria
- Deidentified participant-level data and associated metadata will be uploaded into the Emory Dataverse (https://dataverse.unc.edu/dataverse/Emory).
Deidentified data will be available for sharing. This will include deidentified participant-level demographic characteristics, intervention assignment, and enrollment/non-enrollment status within the parent trial. This will include a de-identified data spreadsheet, readme file, and a data dictionary.