NCT03243071

Brief Summary

The purpose pf this study is to evaluate the comparative effectiveness of a culturally and linguistically tailored clinical trial literacy website in increasing likelihood of participating in clinical trials. To achieve this objective,a randomized group design will address the following patient-centered outcomes: willingness to enroll in clinical trials and behavioral intent as well as likelihood of referring others to enroll in such trials) before and after exposure to a culturally-tailored clinical trial literacy website. Health literacy will be measured both before and post exposure to tailored messages. Participants will be randomized into two groups. The intervention group (n=50) will have access to culturally tailored website. Participants in the control group (n=50) will have access to NYU 's standard trial participation website.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
112

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 2, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 8, 2017

Completed
6 days until next milestone

Study Start

First participant enrolled

August 14, 2017

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 28, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 28, 2019

Completed
2.8 years until next milestone

Results Posted

Study results publicly available

February 1, 2022

Completed
Last Updated

February 1, 2022

Status Verified

January 1, 2022

Enrollment Period

1.5 years

First QC Date

August 2, 2017

Results QC Date

September 27, 2021

Last Update Submit

January 28, 2022

Conditions

Keywords

Medical CareRacial DiscriminationPoor Health LiteracyMedical Care Disparities

Outcome Measures

Primary Outcomes (6)

  • ACTNOW! Clinical Trial Knowledge Assessment Score

    26 statements involved in assessing the participants' knowledge of clinical trials. The total range of score is 0-104; the higher the score, the higher the level of knowledge.

    Baseline

  • Clinical Trial Knowledge Assessment Score

    26 statements involved in assessing the participants' knowledge of clinical trials. The total range of score is 0-104; the higher the score, the higher the level of knowledge.

    Month 1

  • Clinical Trial Knowledge Assessment Score

    26 statements involved in assessing the participants' knowledge of clinical trials. The total range of score is 0-104; the higher the score, the higher the level of knowledge.

    Month 3

  • ACTNOW! Self-Efficacy Score

    A 4-item perceived effectiveness scale was used to assess the perceived persuasiveness of the message. The total range of score is 0-16; the higher the score, the higher the level of self-efficacy.

    Baseline

  • Self-Efficacy Score

    A 4-item perceived effectiveness scale, adapted from Fishbein et al. (2002) was used to assess the perceived persuasiveness of the message. The total range of score is 0-16; the higher the score, the higher the level of self-efficacy.

    Month 1

  • Self-Efficacy Score

    A 4-item perceived effectiveness scale, adapted from Fishbein et al. (2002) was used to assess the perceived persuasiveness of the message. The total range of score is 0-16; the higher the score, the higher the level of self-efficacy.

    Month 3

Study Arms (2)

Intervention Group

EXPERIMENTAL

The intervention group will have access to culturally tailored website.

Behavioral: Tailored Website

Control Group

ACTIVE COMPARATOR

Participants in the control group will have access to NYU 's standard trial participation website.

Behavioral: Standard Website

Interventions

Participants randomized to the intervention arm will have free access to a password protected interactive culturally and linguistically tailored website via a tablet device. No private identifiable data about you will be collected. Participants will receive a brief 10-minute tutorial by a trained research assistant on login procedures and use of the website.

Intervention Group

Participants randomized to the control condition will have free access to the NYU standard clinical trials website. Participants in the control condition will have access to the tailored website at the date of study completion (no later than 6 months' post-date of enrollment).

Control Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Self-reported race/ethnicity as African American, African, Caribbean American or black men and women
  • accessible by telephone
  • no plans to move away from the region within the year following enrollment; consent to participate.

You may not qualify if:

  • Progressive medical illness in which disability or death is expected within one year
  • impaired cognitive or functional ability, which would preclude meaningful participation in the study
  • stated intention to move within the same year of enrollment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York University School of Medicine

New York, New York, 10016, United States

Location

Related Publications (1)

  • Chung A, Seixas A, Williams N, Senathirajah Y, Robbins R, Newsome Garcia V, Ravenell J, Jean-Louis G. Development of "Advancing People of Color in Clinical Trials Now!": Web-Based Randomized Controlled Trial Protocol. JMIR Res Protoc. 2020 Jul 14;9(7):e17589. doi: 10.2196/17589.

MeSH Terms

Conditions

Racism

Condition Hierarchy (Ancestors)

PrejudiceSocial BehaviorBehaviorSocial Discrimination

Results Point of Contact

Title
Girardin Jean-Louis, PhD
Organization
NYU Langoen Health

Study Officials

  • Girardin Jean-Louis, Ph.D.

    NYU Langone Health

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 2, 2017

First Posted

August 8, 2017

Study Start

August 14, 2017

Primary Completion

January 28, 2019

Study Completion

April 28, 2019

Last Updated

February 1, 2022

Results First Posted

February 1, 2022

Record last verified: 2022-01

Locations