Assessment of Kidney Function in Patients With Epilepsy

NCT07288788 | Recruiting

• 1 other identifier: Soh-Med--25-9-2MS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 2

Brief Summary

This observational cross-sectional study aims to assess kidney function in pediatric patients with epilepsy attending Sohag University Hospital. The study evaluates renal biochemical markers, urinalysis, liver functions, abdominal ultrasonography, and the possible renal effects of long-term antiepileptic drug (AED) therapy.

Conditions

Epilepsy

Outcome Measures

Primary Outcomes (1)

• Serum creatinine level in pediatric epilepsy patients

  Measurement of serum creatinine in pediatric patients at enrollment to assess renal function related to epilepsy or antiepileptic drug use

  At enrollment (single cross-sectional assessment)

Secondary Outcomes (5)

• Prevalence of nephrolithiasis / nephrocalcinosis

  At enrollment (single cross-sectional assessment)

• Electrolyte disturbances

  At enrollment (single cross-sectional assessment)

• Abnormal urinalysis findings

  At enrollment (single cross-sectional assessment)

• Association between AED regimen and renal parameters

  At enrollment (single cross-sectional assessment)

• Abdominal Ultrasound Findings

  At enrollment (single cross-sectional assessment)

Study Arms (1)

All Participants

Observational study of pediatric patients admitted to Sohag University Hospital

Behavioral: Standard Clinical Observation

Interventions

Standard Clinical Observation BEHAVIORAL

Observational study of pediatric patients admitted to Sohag University Hospital. No experimental treatment or device is administered. Data collection only.

All Participants

Eligibility Criteria

• Age: 1 Month - 15 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Pediatric patients admitted to Sohag University Hospital. Observational data will be collected from medical records.

You may qualify if:

• Age: children between 1month and 15years old.
• Both sexes.
• children who suffering from idiopathic epilepsy

You may not qualify if:

• Age: children below 1month old\& children above 15 years old.
• Children suffer from convulsions due to CNS infection
• Children with non idiobathic epilepsy

Sponsors & Collaborators

• Sohag University: lead

Study Sites (2)

Sohag University

Sohag, Egypt

RECRUITING

Sohage Faculty of Medicine

Sohag, Egypt

ACTIVE NOT RECRUITING

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Central Study Contacts

mohamed hassan hassan, resident

CONTACT

01146167336; Mohamedhassanfonn2@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Physician, Pediatrics

Study Record Dates

• First Submitted: November 21, 2025
• First Posted: December 17, 2025
• Study Start: September 28, 2025
• Primary Completion: September 28, 2025
• Study Completion (Estimated): September 28, 2026
• Last Updated: December 17, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will share

Locations

EG (2)