Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in HairTransplantation

NCT07287579 | Not Yet Recruiting DMC

• 1 other identifier: Soh-Med--25-11-1MD
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

• To compare the efficacy of platlet rich plasma and Nanofat injection as adjuvant therapies with FUE hair transplantation in improving graft survival rate,
• To measure hair density and thickness postoperatively using dermoscopy or trichoscopy.
• To evaluate patient satisfaction and photographic assessment by blinded evaluators.
• To assess any adverse effects or complications related to each modality

Conditions

Androgenic Alopecia

Keywords

hair transplantation

Outcome Measures

Primary Outcomes (1)

• • To measure hair density using dermoscopy.

  To measure how many hair follicles in each cubic centimetre

  • All patients will be followed up about 6-12 months postoperative.

Study Arms (3)

group a

EXPERIMENTAL

hair transplantation done alone without platelet rich plasma or nanofat injection

Procedure: hair transplantation

group b

EXPERIMENTAL

we do injection of platelet rich plasma with hair transplantation

Procedure: hair transplantation

group c

EXPERIMENTAL

we do injection of nanofat with hair transplantation

Procedure: hair transplantation

Interventions

hair transplantation PROCEDURE

we compare the effect of nanofat injection and platelet rich plasma in hair transplantation in male androgenic alopecia

Also known as: hair transplantation with platelet rich plasma, hair transplantation with nanofat injection

group a; group b; group c

Eligibility Criteria

• Age: 20 Years - 50 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• \. Male patients with stable androgenic alopecia more than 2 years. 2. Age 20-50 years 3. No recent medical hair loss treatments.

You may not qualify if:

• \. Active scalp infections or scarring alopecia. 2. Systemic diseases affecting wound healing. 3. Platelet disorders or anticoagulant use. 4. Smoking or heavy alcohol intake

Sponsors & Collaborators

• Sohag University: lead

Related Publications (1)

• Evin N, Guray Evin S. Camouflage of Postburn Scarring Alopecia Using Nanofat Grafting and Follicular Unit Hair Transplantation. Plast Reconstr Surg. 2024 Jul 1;154(1):207-215. doi: 10.1097/PRS.0000000000010759. Epub 2023 May 26.

  PMID: 37253046 BACKGROUND

Related Links

• Outcome of Intra-operative Injected Platelet-rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomised Study in Forty Patients

MeSH Terms

Conditions

Alopecia

Condition Hierarchy (Ancestors)

Hypotrichosis; Hair Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Study Officials

• samia saied, MD

  Sohag University

  STUDY CHAIR

Central Study Contacts

shenouda Faiez, AL

CONTACT

0201285122844; shenoda011111@med.sohag.edu.eg

mostafa haredy, MD

CONTACT

0201095159392; mostafaharedy84@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer in plastic surgery department, faculty of medicine Sohag University hospital.

Study Record Dates

• First Submitted: November 22, 2025
• First Posted: December 17, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: December 17, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share