Condensed Nanofat Grafting for Treatment of Androgenetic Alopecia
1 other identifier
interventional
10
1 country
1
Brief Summary
Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc. In this clinical trial, the investigators aim to analyze the effect of nanofat grafting on treating androgenic alopecia in male.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2019
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 14, 2018
CompletedFirst Posted
Study publicly available on registry
April 24, 2018
CompletedStudy Start
First participant enrolled
February 27, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 27, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2020
CompletedFebruary 21, 2021
February 1, 2021
1 year
April 14, 2018
February 17, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Dermatoscope
the density of hair follicle and diameter of hair will be analized by dermatoscope before and after the treatment of Nanofat grafting.
Baseline and at1,3,6,9,12 months after the treatment
Other Outcomes (1)
Satisfaction assessments
1,3,6,12 months after treatment
Study Arms (1)
processed Nanofat grafting
EXPERIMENTALprocessed autologous Nanofat will be injected into the area of the scalp with androgenic alopecia.
Interventions
hair loss area will be treated by processed autologous Nanofat grafting
Eligibility Criteria
You may qualify if:
- Male patients with androgenic alopecia aging from 18 to 50.
- No scars and wounds on the alopecia area.
- No skin disease or serious cardiovascular disease.
- Preoperative examinations remain healthy.
You may not qualify if:
- Serious chronic heart, liver, kidney, blood system disease
- Allergic diseases, skin inflammation or wounds
- Alopecia but not androgenic alopecia
- Acute or chronic infection
- Take anticoagulant drugs
- Active vitiligo, psoriasis, systemic lupus erythematosus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
the first affiliated hospital of Jinan University
Guangzhou, Guangdong, 510000, China
Related Publications (3)
Tonnard P, Verpaele A, Peeters G, Hamdi M, Cornelissen M, Declercq H. Nanofat grafting: basic research and clinical applications. Plast Reconstr Surg. 2013 Oct;132(4):1017-1026. doi: 10.1097/PRS.0b013e31829fe1b0.
PMID: 23783059BACKGROUNDWon CH, Park GH, Wu X, Tran TN, Park KY, Park BS, Kim DY, Kwon O, Kim KH. The Basic Mechanism of Hair Growth Stimulation by Adipose-derived Stem Cells and Their Secretory Factors. Curr Stem Cell Res Ther. 2017;12(7):535-543. doi: 10.2174/1574888X12666170829161058.
PMID: 28875863BACKGROUNDGu Z, Li Y, Li H. Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars. JAMA Facial Plast Surg. 2018 Mar 1;20(2):128-135. doi: 10.1001/jamafacial.2017.1329.
PMID: 28975248BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- professor
Study Record Dates
First Submitted
April 14, 2018
First Posted
April 24, 2018
Study Start
February 27, 2019
Primary Completion
February 27, 2020
Study Completion
May 1, 2020
Last Updated
February 21, 2021
Record last verified: 2021-02
Data Sharing
- IPD Sharing
- Will not share