Efficacy of Subclavian Vein/Artery Diameter Index in Predicting the Incidence of the Spinal-Induced Hypotension in Geriatric Patients

NCT07286422 | Not Yet Recruiting DMC

• 1 other identifier: SCV with hypotension
• Study Type: observational
• Target: 107
• Locations: 1 country
• Sites: 1

Brief Summary

The hypothesis of the study will be that the subclavian vein/subclavian artery diameter (SCVD/SCAD) index will be a good predictor of spinal-induced hypotension in geriatric patients.

Conditions

Spinal Induced Hypotension; Old Age; Debility

Outcome Measures

Primary Outcomes (1)

• subclavian vein to artery index

  The index will be calculated as the ratio between the SCV maximum diameter and the SAD diameter.

  pre-anesthesia peroid

Interventions

Assessment of the SCV & SCA DIAGNOSTIC_TEST

The right SCV was measured using a linear array probe, placed in the sagittal plane at the deltopectoral triangle (beneath the proximal part of the middle of the clavicle and the area below the clavicle). In M-mode, measurements of SCV internal anteroposterior diameter, which is maximum during expiration (SCVmax) and minimum during inspiration (SCVmin), were taken in one respiratory cycle. Ultrasound scan of the patient's supraclavicular area showing the subclavian artery. The index was calculated as the ratio between the SCV maximum diameter and the SAD diameter

Assessment of the IVC and aorta DIAGNOSTIC_TEST

The IVC measurement will be obtained in the M-mode scan using a curvilinear (3.5 to 5 MHz) ultrasound transducer. The transducer was placed longitudinally in the subxiphoid region. The IVC maximum and minimum anterior-posterior diameters were obtained just distal to the IVC-hepatic vein junction. In M-mode, measurements of IVC internal anteroposterior diameter, which is maximum during expiration (IVCmax) and minimum during inspiration. IVCmin), were taken in one respiratory cycle. The abdominal aorta was identified to the left of the IVC, 10 mm above the coeliac trunk. The maximum internal anterior-posterior diameter of the aorta was obtained during systole. The caval /aorta diameter index was calculated as the ratio between the IVC maximum diameter and the aortic diameter. The index had a sensitivity of 96%, a specificity of 88%, and an accuracy of 95% to predict PSAH at a cut-off point of less than 1.2

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

107 geriatric patients, aged 65 or older, scheduled for elective surgery under spinal anesthesia

You may qualify if:

• \. Patients aged 65 or older. 2. Lower body surgeries to be done with spinal anesthesia. 3. BMI less than 30 kg/m2. 4. Patients with ASA I-III.

You may not qualify if:

• \- 1. Patient refusal. 2. Patients with a history of peripheral arterial disease or atherosclerosis 3. Patients with a body mass index of greater than 30 kg/m2 4. Major bloody surgeries (class C surgeries) 5. Patients with a history of cardiovascular disorders, including arrhythmias, heart failure, tricuspid or mitral regurgitation, dilated right atrium or ventricle, AF, ejection fraction \< 45%, uncontrolled hypertension, systolic blood pressure \<90 mmHg, dyspnea, agitation.
• \. Patients with increased intra-abdominal pressure, intra-abdominal mass compressing the IVC.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

tarek Abdelhay Mostafa

Tanta, El Gharbyia, 31111, Egypt

Location

MeSH Terms

Conditions

Frailty

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

tarek AH Mostafa

CONTACT

01003591332; dr.tarek311@yahoo.com

sameh Ahmed

CONTACT

samehabdelkhalik1982@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator

Study Record Dates

• First Submitted: December 2, 2025
• First Posted: December 16, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: December 16, 2025

Record last verified: 2025-12

Locations

EG (1)