Contralateral Adrenal Volume Predicts Duration of Postoperative Steroid Replacement Therapy in Non-ACTH-dependent Hypercortisolism

NCT07282223 | Completed DMC

• 1 other identifier: PKUFH-CS-CAV-001
• Study Type: observational
• Target: 121
• Locations: 1 country
• Sites: 1

Brief Summary

To identify preoperative factors influencing the duration of steroid replacement therapy after adrenalectomy/adrenal-sparing surgery in patients with non-ACTH-dependent hypercortisolism.

Conditions

Glucocorticoid; Prediction; Cushing's Syndrome; Postoperative

Outcome Measures

Primary Outcomes (1)

• Tumor volume

  from 2017 to 2025

Interventions

observational diagnostic model development OTHER

observational diagnostic model development

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

In all, 111 patients (meadian age: 54years; 64.9% female) were included and received postoperative steroid replacement therapy, among whom 65 were diagnosed with subclinical Cushing's syndrome (SCS) and 46 with overt Cushing's syndrome (CS).

You may qualify if:

• In all, 111 patients (meadian age: 54years; 64.9% female) were included and received postoperative steroid replacement therapy, among whom 65 were diagnosed with subclinical Cushing's syndrome (SCS) and 46 with overt Cushing's syndrome (CS).

You may not qualify if:

• none

Sponsors & Collaborators

• Peking University First Hospital: lead

Study Sites (1)

Department of Urology, Peking University First Hospital, Beijing, 100034

Beijing, China

Location

MeSH Terms

Conditions

Cushing Syndrome

Condition Hierarchy (Ancestors)

Adrenocortical Hyperfunction; Adrenal Gland Diseases; Endocrine System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 2, 2025
• First Posted: December 15, 2025
• Study Start: August 1, 2017
• Primary Completion: April 1, 2025
• Study Completion: April 1, 2025
• Last Updated: December 15, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will share

Locations

CN (1)