Effect of the Quadratus Lumborum Block Versus the Lumbar Plexus for Spiral Thighplasty Surgery

NCT07280182 | Completed

• 2 other identifiers: 11/2025ANET2Menoufia University
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

Whether trans muscular QLB provides postoperative analgesia compared with LPB after thigh lift surgery

Conditions

Analgesia

Keywords

spiral thighplasty , pain , nerve block

Outcome Measures

Primary Outcomes (1)

• Visual analogue scale score

  Visual analogue scale score at 1st,6th,12th and 24 h (where 0 is interpreted as no pain, 1-4 mild pain, 5-6 moderate pain, 7-10 severe pain)

  24 hours

Secondary Outcomes (6)

• Time for first analgesic request

  24 hours

• Opioid consumption

  24 hours

• Time to walk >30 (meter)

  24 hours

• Performance Time

  minutes

• The number of patients who develop block-related complications

  24 hours

Study Arms (2)

Group QLB

OTHER

Ultrasound-Guided Trans-muscular QLB

Other: Ultrasound-Guided Trans-muscular QLB

Group LPB

OTHER

Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block

Other: Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block

Interventions

Ultrasound-Guided Trans-muscular QLB OTHER

With the patient lateral decubitus position, a low-frequency curvilinear probe in the 'Shamrock' view at L2-L4. In-plane posterior-to-anterior needle advancement through the Quadratus lumborum to the interfascial plane anterior to QL and posterior to Psoas major. Inject 30 mL Bupivacaine 0.25% after negative aspiration and hydrodissection to confirm proper spread . Then the patient will be turned to the other side, and the block will be done with the same technique

Group QLB

Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block OTHER

Lateral decubitus, Shamrock view to identify the Psoas compartment; in-plane needle advancement to the Psoas compartment adjacent to the transverse process. Inject 30 mL of Bupivacaine 0.25% in 5 mL increments, aspirating frequently. This will be done in the same position for both sides

Group LPB

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• ASA ( American Society of Anaesthesia) I-II
• elective bilateral spiral thigh lift under general anesthesia
• consent to regional block and trial participation

You may not qualify if:

• Coagulopathy or therapeutic anticoagulation not meeting ASRA safety windows
• infection at injection sites
• allergy to local anesthetics
• preexisting significant neuropathy
• BMI \> 35 kg/m² if impeding ultrasound visualization; renal/hepatic failure; pregnancy; inability to use NRS; chronic opioid use \>60 mg oral morphine equivalents/day; contraindication to study analgesics.

Sponsors & Collaborators

• Menoufia University: lead

Study Sites (1)

Faculty of medicine,Menofia university hospitals

Cairo, Shibin El Kom, 32511, Egypt

Location

MeSH Terms

Conditions

Agnosia; Pain

Interventions

Dental Occlusion

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena

Study Officials

• AMAL G SAFAN, MD

  Menoufia University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: Computer-generated randomization in variable blocks; allocation sealed in opaque envelopes. Blocks performed by an anesthesiologist not involved in postoperative assessment. Patients and outcome assessors are blinded. Drape and opaque dressings conceal injection sites for both groups to preserve blinding
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer

Model Details: Prospective, randomized, parallel-group, double-blind, clinical trial. Primary endpoint: time for first analgesic request postoperatively. Key secondary endpoints: 24-hour opioid consumption (oral morphine equivalents), pain on movement at 6/12/24 hours, time to first ambulation, postoperative nausea/vomiting (PONV), block performance time, and block-related complications. Hypothesis: QLB is non-inferior to LPB for 24-hour pain scores and will yield less motor weakness

Study Record Dates

• First Submitted: November 28, 2025
• First Posted: December 12, 2025
• Study Start: December 13, 2025
• Primary Completion: February 28, 2026
• Study Completion: March 14, 2026
• Last Updated: March 17, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)