Incidental Findings on Coronary Computed Tomography Angiography

NCT07275281 | Not Yet Recruiting

• 1 other identifier: JOINCIDENT.CCTA.NOV2025/3
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Coronary CT angiography (CCTA) is increasingly used for ischemic heart disease diagnosis. The rising number of CCTA tests has led to a significant increase in the number of finding unexpected incidental extracardiac diseases.

Conditions

Computed Tomography; Coronary Angiography; Incidental Findings

Keywords

Coronary artery disease; computed tomography; indidental findings

Outcome Measures

Primary Outcomes (3)

• Non atherosclerotic coronary disease

  Findings other than coronary atherosclerotic disease: coronary bridge, coronary dissection, coronary embolism, and coronary fistula.

  BASELINE

• Non coronary cardiac findings

  Findings include valve calcifications, left atrial appendage thrombus, patent foramen ovale and septal defects, pericardial effusion, LV clots, cardiac tumors.

  BASELINE

• Non cardiac findings

  Non cardiac findings include: a. major vascular abnormalities in the aorta and the pulmonary arteries, b. pulmonary disease: masses, lymph nodes, granulomas, and pleural effusion, and c. non pulmonary findings in the diaphragm and the hepatobiliary tree.

  BASELINE

Study Arms (1)

Adult patients who underwent CCTA

All adults (18 years of age and older0 who underwent CCTA to evaluate the coronary arteries in the past 5 years will have their CT scans reviewed for the presence of non coronary incidental findings.

Diagnostic Test: CCTA (Review of the scans)

Interventions

CCTA (Review of the scans) DIAGNOSTIC_TEST

Reviewing coronary scans done in the past 5 years looking for findings other than atherosclerotic coronary artery disease.

Adult patients who underwent CCTA

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

1. All adult patients who underwent CCTA for chest pain diagnosis. 2. Scans will be reviewed seeking the presence of coronary non atherosclerotic disease in the coronaries, cardiac structure and non cardiac structures.

You may qualify if:

• Adult patients ho underwent CCTA

You may not qualify if:

• None

Sponsors & Collaborators

• Jordan Collaborating Cardiology Group: lead

Study Sites (1)

Istishari Hospital

Amman, 11184, Jordan

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Central Study Contacts

Wasfi Alghween, MD

CONTACT

+96265001000; hammoudeh_ayman@yahoo.com

Musa Saadeh

CONTACT

065001000

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 28, 2025
• First Posted: December 10, 2025
• Study Start: January 2, 2026
• Primary Completion (Estimated): January 2, 2027
• Study Completion (Estimated): February 28, 2027
• Last Updated: December 30, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP

Locations

JO (1)