Assessment of Pentraxin Levels in the Gingival Fluid of Abutment Teeth in the Context of the Use of Fixed Dentures

NCT07271563 | Completed

• 1 other identifier: 1072.6120.131.2023
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The use of fixed dentures in prosthetic treatment requires a thorough analysis of clinical factors such as: the condition of the abutments subject to grinding procedures, the degree of their loosening, the extent of missing teeth, and the condition of the periodontal tissues. An important step in prosthetic treatment is planning subsequent procedures, including the grinding of the crowns of the natural teeth. Often, the initial stages of gingivitis are not visible during a clinical examination \[1-4\].

Conditions

Periodontal Disease; Periodontal Diseases; Prosthodontics

Outcome Measures

Primary Outcomes (1)

• Concentration of pentraxine

  March 2023- August 2024

Interventions

Diagnostic Pentraxine test DIAGNOSTIC_TEST

Diagnostic test - in order to measure Pantraxine level in gingival fluid was performed.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study material consist of 90 patients, of both sexes, aged between 35-48 years, who report for prosthetic treatment with fixed dentures to the University Dental Clinic at the Institute of Dentistry in Krakow, in the period: March 2023- August 2024.

You may qualify if:

• appropriate age range of patients, indication for the use of fixed dentures, no signs of gingivitis in the clinical examination

You may not qualify if:

• any autoimmune disease or other systemic disease which could alter the course of periodontal disease, the desire to withdraw from participation in the research and the occurrence of general and local diseases

Sponsors & Collaborators

• Jagiellonian University: lead

Study Sites (1)

Dental Institute

Krakow, 31-155, Poland

Location

MeSH Terms

Conditions

Periodontal Diseases

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: November 15, 2025
• First Posted: December 9, 2025
• Study Start: March 1, 2023
• Primary Completion: August 1, 2024
• Study Completion: August 1, 2024
• Last Updated: December 9, 2025

Record last verified: 2025-12

Locations

PL (1)