Effect of Bicycle Ergometer Training on Fat Tissue Amount and Metabolism

NCT07263126 | Recruiting

• 1 other identifier: 23.07.2024/13
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the effect of endurance training performed with a bicycle ergometer at different ambient temperatures on the amount of fat tissue and fat tissue metabolism in overweight and obese women.

Conditions

Endurance Training

Keywords

Bicycle Ergometer; Overweight; Obese

Outcome Measures

Primary Outcomes (5)

• rate of BMI

  assesed with height and body weight

  baseline/ through study completion, an average 3 months

• analysis of biyoelectric impedans Bioelectrical impedance analysis

  assesed with with a Tanita BC 418 brand device.

  baseline/ through study completion, an average 3 months

• Ratio of waist-hip Waist hip ratio

  Waist and hip circumference will be measured with a tape measure.

  baseline/ through study completion, an average 3 months

• rate of subcutaneous and visceral adipose tissue thickness

  assesed with Ultrasonography

  baseline/ through study completion, an average 3 months

• concentration of serum irisin, leptin, adiponectin, apelin, İL-6 and FGF-21

  assesed with blood analysis

  baseline/ through study completion, an average 3 months

Study Arms (3)

Case group 1

EXPERIMENTAL

participants trained in termoneutral ambient temperature

Other: endurance training with bicycle ergometer in termoneutral ambient temperature

Case group 2

ACTIVE COMPARATOR

participants trained in lightly cold ambient temperature

Other: endurance training with bicycle ergometer in lightly cold ambient temperature

control group

NO INTERVENTION

participants do not trained

Interventions

endurance training with bicycle ergometer in termoneutral ambient temperature OTHER

trained with bicycle ergometer three times a week for three months.

Case group 1

endurance training with bicycle ergometer in lightly cold ambient temperature OTHER

trained with bicycle ergometer three times a week for three months.

Case group 2

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Being female,
• Being between 20-40 years old,
• Having a BMI between 25 and 34.9,
• Having a waist circumference greater than 80 cm,
• Not having participated in any exercise program in the last 3 months ,
• Not having experienced a change of more than 10% in body weight in the last 6 months.

You may not qualify if:

• On a weight loss diet,
• Having cancer, unstable heart disease, cerebrovascular disease, metabolic disease, diabetes, hypertension, psychiatric disorders, or other conditions or neurological disorders,
• Having a musculoskeletal disorder or any disease/injury that may affect participation in exercise training,
• Participating in regular physical activity (at least 150 minutes of moderate-intensity physical activity or 75 minutes of vigorous-intensity physical activity or an equivalent combination of both during the week),
• Being pregnant or breastfeeding,
• Having undergone surgery for the treatment of obesity,
• Receiving pharmacological treatment for obesity. Participants who did not attend more than 20% of the endurance training program will be excluded from the study.

Sponsors & Collaborators

• Pamukkale University: lead

Study Sites (1)

Şule Şimşek

Denizli, Sarayköy, 09200, Turkey (Türkiye)

RECRUITING

Related Publications (1)

• Otero-Diaz B, Rodriguez-Flores M, Sanchez-Munoz V, Monraz-Preciado F, Ordonez-Ortega S, Becerril-Elias V, Baay-Guzman G, Obando-Monge R, Garcia-Garcia E, Palacios-Gonzalez B, Villarreal-Molina MT, Sierra-Salazar M, Antuna-Puente B. Exercise Induces White Adipose Tissue Browning Across the Weight Spectrum in Humans. Front Physiol. 2018 Dec 11;9:1781. doi: 10.3389/fphys.2018.01781. eCollection 2018.

  PMID: 30618796 RESULT

MeSH Terms

Conditions

Overweight; Obesity

Interventions

Endurance Training

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Ummuhan Baş Aslan, Prof. Dr.

  Prof. Dr.

  STUDY DIRECTOR

Central Study Contacts

Şule Şimşek, Ass. Prof.

CONTACT

05058099914; sules@pau.edu.tr

Ayşe Nur Oymak Soysal, PhD

CONTACT

05058446603; aysenuroymak@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: The main outcome measures will be assessed by 3 different researchers . The researchers conducting the assessments will not know which group the participants are belongs to.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal İnvestigator

Model Details: Endurance training in termoneutral ambient, Endurance training in lightly cold ambient, control group (the waiting list group)

Study Record Dates

• First Submitted: May 27, 2025
• First Posted: December 4, 2025
• Study Start: May 27, 2025
• Primary Completion (Estimated): May 27, 2026
• Study Completion (Estimated): May 27, 2026
• Last Updated: December 4, 2025

Record last verified: 2025-12

Locations

TU (1)